C8G antibody (N-Term)

Catalog No. ABIN2776987

This Rabbit Polyclonal antibody specifically detects C8G in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Horse, Pig, Rabbit, Cow and Guinea Pig.

Quick Overview for C8G antibody (N-Term) (ABIN2776987)

Target: C8G (Complement Component 8, gamma Polypeptide (C8G))

Reactivity: Human, Mouse, Rat, Dog, Horse, Pig, Rabbit, Cow, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C8G antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-C8G Antibody

Binding Specificity: N-Term

Purpose: C8G Antibody - N-terminal region

Sequence: VGSACRFLQE QGHRAEATTL HVAPQGTAMA VSTFRKLDGI CWQVRQLYGD

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 85%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against C8G. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human C8G

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP41773-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for C8G

Target: C8G (Complement Component 8, gamma Polypeptide (C8G))

Alternative Name: C8G

Background:

Background Information: The protein encoded by this gene belongs to the lipocalin family. It is one of the three subunits that constitutes complement component 8 (C8), which is composed of a disulfide-linked C8 alpha-gamma heterodimer and a non-covalently associated C8 beta chain. C8 participates in the formation of the membrane attack complex (MAC) on bacterial cell membranes. While subunits alpha and beta play a role in complement-mediated bacterial killing, the gamma subunit is not required for the bactericidal activity.

Gene Name: complement component 8, gamma polypeptide

Alternative Symbols: C8C

Protein Name: Complement component C8 gamma chain

Molecular Weight: 22kDa

Gene ID: 733

NCBI Accession: NP_000597

UniProt: P07360

Pathways: Complement System