OXT antibody (N-Term)

Catalog No. ABIN2777015

This anti-OXT antibody is a Rabbit Polyclonal antibody detecting OXT in WB. Suitable for Human, Rat, Mouse, Cow, Dog, Guinea Pig, Horse, Rabbit and Sheep.

Quick Overview for OXT antibody (N-Term) (ABIN2777015)

Target: OXT (Oxytocin, Prepropeptide (OXT))

Reactivity: Human, Rat, Mouse, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OXT antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-OXT Antibody

Binding Specificity: N-Term

Sequence: LGLLALTSAC YIQNCPLGGK RAAPDLDVRK CLPCGPGGKG RCFGPNICCA

Predicted Reactivity: Cow: 85%, Dog: 92%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 79%, Rabbit: 86%, Rat: 93%, Sheep: 85%

Characteristics: This is a rabbit polyclonal antibody against OXT. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 125 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for OXT

Target: OXT (Oxytocin, Prepropeptide (OXT))

Alternative Name: OXT

Background: There are two proteins encoded by this gene, oxytocin and neurophysin I. Oxytocin is posterior pituitary hormone which is synthesized as an inactive precursor in the hypothalamus along with its carrier protein neurophysin I. Together with neurophysin, it is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis, where it is either stored or secreted into the bloodstream. The precursor seems to be activated while it is being transported along the axon to the posterior pituitary. This hormone contracts smooth muscle during parturition and lactation. It is also involved in cognition, tolerance, adaptation and complex sexual and maternal behaviour, as well as in the regulation of water excretion and cardiovascular functions.
Alias Symbols: MGC126890, MGC126892, OT, OT-NPI
Protein Interaction Partner: TXNDC17, ESR2, PREP, OXTR, KMT2A,
Protein Size: 125

Molecular Weight: 9 kDa

Gene ID: 5020

NCBI Accession: NM_000915, NP_000906

UniProt: P01178

Pathways: Myometrial Relaxation and Contraction, Feeding Behaviour