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LSS antibody (Middle Region)

LSS Reactivity: Human, Mouse, Rat, Rabbit, Cow, Zebrafish (Danio rerio), Dog, Guinea Pig, Horse WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2777021
  • Target See all LSS Antibodies
    LSS (Lanosterol Synthase (2,3-Oxidosqualene-Lanosterol Cyclase) (LSS))
    Binding Specificity
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 17
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Rabbit, Cow, Zebrafish (Danio rerio), Dog, Guinea Pig, Horse
    Host
    • 16
    • 2
    Rabbit
    Clonality
    • 16
    • 2
    Polyclonal
    Conjugate
    • 11
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This LSS antibody is un-conjugated
    Application
    • 8
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    KCPHVTEHIP RERLCDAVAV LLNMRNPDGG FATYETKRGG HLLELLNPSE
    Predicted Reactivity
    Cow: 100%, Dog: 86%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 93%, Zebrafish: 100%
    Characteristics
    This is a rabbit polyclonal antibody against LSS. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human LSS
    Top Product
    Discover our top product LSS Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 732 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    LSS (Lanosterol Synthase (2,3-Oxidosqualene-Lanosterol Cyclase) (LSS))
    Alternative Name
    LSS (LSS Products)
    Synonyms
    OSC antibody, 2810025N20Rik antibody, BC029082 antibody, D10Ertd116e antibody, Osc antibody, xlss antibody, Tb07.27E10.490 antibody, NCU01119.1 antibody, lanosterol synthase antibody, lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) antibody, putative lanosterol synthase antibody, Lanosterol synthase, putative antibody, LSS antibody, Lss antibody, lss antibody, CND02520 antibody, Tc00.1047053506825.170 antibody, Tc00.1047053508175.70 antibody, Tb927.7.5230 antibody, NCU01119 antibody, LMJF_06_0650 antibody, CGB_D5080W antibody, LOC100636608 antibody
    Background
    LSS catalyzes the conversion of (S)-2,3 oxidosqualene to lanosterol. It is a member of the terpene cyclase/mutase family and catalyzes the first step in the biosynthesis of cholesterol, steroid hormones, and vitamin D. Two transcript variants encoding the same protein have been found for this gene.The protein encoded by this gene catalyzes the conversion of (S)-2,3 oxidosqualene to lanosterol. The encoded protein is a member of the terpene cyclase/mutase family and catalyzes the first step in the biosynthesis of cholesterol, steroid hormones, and vitamin D. Two transcript variants encoding the same protein have been found for this gene.
    Alias Symbols: OSC
    Protein Interaction Partner: UBC, SUMO1, NEDD8, ATP4A, NR4A1,
    Protein Size: 732
    Molecular Weight
    83 kDa
    Gene ID
    4047
    NCBI Accession
    NM_002340, NP_002331
    UniProt
    P48449
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