DAO antibody (C-Term)

Catalog No. ABIN2777059

Cited in 1 publication. The Rabbit Polyclonal anti-DAO antibody (ABIN2777059) specifically detects DAO in WB and IHC. The antibody is reactive with Human, Rat, Pig, Mouse, Cow, Horse, Dog, Guinea Pig, Rabbit and Zebrafish (Danio rerio) samples.

Quick Overview for DAO antibody (C-Term) (ABIN2777059)

Target: DAO (ABP1) (Amiloride Binding Protein 1 (Amine Oxidase (Copper-Containing)) (ABP1))

Reactivity: Human, Rat, Pig, Mouse, Cow, Horse, Dog, Guinea Pig, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DAO antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-DAO Antibody

Binding Specificity: C-Term

Purpose: ABP1 Antibody - C-terminal region

Sequence: QFLHNNENIE NEDLVAWVTV GFLHIPHSED IPNTATPGNS VGFLLRPFNF

Predicted Reactivity: Cow: 86%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 92%, Pig: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against ABP1. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human ABP1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP41908-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-DAO antibody (ABIN2777059)

Liang, Zhao, Deng, Tian, Lei, Xu, Zhang, Su, Yang: "Estrogen regulates amiloride-binding protein 1 through CCAAT/enhancer-binding protein-beta in mouse uterus during embryo implantation and decidualization." in: Endocrinology, Vol. 151, Issue 10, pp. 5007-16, (2010) (PubMed).

Target Details for DAO

Target: DAO (ABP1) (Amiloride Binding Protein 1 (Amine Oxidase (Copper-Containing)) (ABP1))

Alternative Name: ABP1

Background:

Background Information: ABP1 is a membrane glycoprotein that is expressed in many epithelium-rich and/or hematopoietic tissues and oxidatively deaminates putrescine and histamine. The protein may play a role in controlling the level of histamine and/or putrescine in these tissues. It also binds to and is inhibited by amiloride, a diuretic that acts by closing epithelial sodium ion channels.This gene encodes a membrane glycoprotein that is expressed in many epithelium-rich and/or hematopoietic tissues and oxidatively deaminates putrescine and histamine. The protein may play a role in controlling the level of histamine and/or putrescine in these tissues. It also binds to and is inhibited by amiloride, a diuretic that acts by closing epithelial sodium ion channels.

Gene Name: Amiloride binding protein 1 (amine oxidase (copper-containing))

Alternative Symbols: ABP, DAO, KAO, ABP1, DAO1

Protein Name: Amiloride-sensitive amine oxidase [copper-containing]

Molecular Weight: 83kDa

Gene ID: 26

NCBI Accession: NP_001082

UniProt: P19801