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KRT8 antibody (Middle Region)

The Rabbit Polyclonal anti-KRT8 antibody has been validated for WB and IHC. It is suitable to detect KRT8 in samples from Human, Rat, Mouse, Cow, Rabbit, Pig, Dog, Guinea Pig and Horse.
Catalog No. ABIN2777113

Quick Overview for KRT8 antibody (Middle Region) (ABIN2777113)

Target

See all KRT8 Antibodies
KRT8 (Keratin 8 (KRT8))

Reactivity

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  • 88
  • 77
  • 66
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Human, Rat, Mouse, Cow, Rabbit, Pig, Dog, Guinea Pig, Horse

Host

  • 169
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  • 3
Rabbit

Clonality

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  • 1
Polyclonal

Conjugate

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  • 27
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  • 12
  • 9
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  • 8
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  • 3
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  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
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This KRT8 antibody is un-conjugated

Application

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Western Blotting (WB), Immunohistochemistry (IHC)
  • Binding Specificity

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    Middle Region

    Sequence

    QSLAGKHGDD LRRTKTEISE MNRNISRLQA EIEGLKGQRA SLEAAIADAE

    Predicted Reactivity

    Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 86%, Rat: 93%

    Characteristics

    This is a rabbit polyclonal antibody against KRT8. It was validated on Western Blot using a cell lysate as a positive control.

    Purification

    Affinity Purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the middle region of human KRT8
  • Application Notes

    Optimal working dilutions should be determined experimentally by the investigator.

    Comment

    Antigen size: 483 AA

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handling Advice

    Avoid repeated freeze-thaw cycles.

    Storage

    -20 °C

    Storage Comment

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target

    KRT8 (Keratin 8 (KRT8))

    Alternative Name

    KRT8

    Background

    KRT8 together with KRT19, help to link the contractile apparatus to dystrophin at the costameres of striated muscle.
    Alias Symbols: CARD2, CK8, CYK8, K2C8, K8, KO, CK-8
    Protein Interaction Partner: KRT31, KRT15, KRT13, KRT40, TFIP11, KRT38, UBC, MDM2, ASB12, EED, GRB2, FBXO25, PAN2, IQCB1, IKBKG, VCAM1, NOS2, KRT18, KPNA2, ITGA4, FN1, ATF2, CDH1, STAM2, CRK, UBASH3B, APEX1, RCHY1, SQSTM1, SUMO1, SUMO2, SUMO3, MAPK8, QRSL1, YWHAQ, TJP1, TADA2A, USP32
    Protein Size: 483

    Molecular Weight

    54 kDa

    Gene ID

    3856

    NCBI Accession

    NM_002273, NP_002264

    UniProt

    P05787
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