VGF antibody (Middle Region)

Catalog No. ABIN2777158

Product Details anti-VGF Antibody

Target: VGF (VGF Nerve Growth Factor Inducible (VGF))

Binding Specificity: Middle Region

Reactivity: Human, Rat, Mouse, Dog, Horse, Pig, Saccharomyces cerevisiae, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VGF antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: VRSPQPPPPA PAPARDELPD WNEVLPPWDR EEDEVYPPGP YHPFPNYIRP

Predicted Reactivity: Dog: 91%, Horse: 85%, Human: 100%, Mouse: 86%, Pig: 85%, Rat: 91%, Yeast: 92%, Zebrafish: 91%

Characteristics: This is a rabbit polyclonal antibody against VGF. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human VGF

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 615 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for VGF

Target: VGF (VGF Nerve Growth Factor Inducible (VGF))

Alternative Name: VGF (VGF Products)

Synonyms: VGF antibody, Gm1052 antibody, VGF nerve growth factor inducible antibody, VGF antibody, Vgf antibody

Background: VGF is specifically expressed in a subpopulation of neuroendocrine cells, and is upregulated by nerve growth factor. It also shares similarities with the secretogranin/chromogranin family, however, its exact function is not known. This gene is specifically expressed in a subpopulation of neuroendocrine cells, and is upregulated by nerve growth factor. The structural organization of this gene is similar to that of the rat gene, and both the translated and the untranslated regions show a high degree of sequence similarity to the rat gene. The encoded secretory protein also shares similarities with the secretogranin/chromogranin family, however, its exact function is not known.
Alias Symbols: -
Protein Interaction Partner: SUZ12, RNF2, PARK2,
Protein Size: 615

Molecular Weight: 65 kDa

Gene ID: 7425

NCBI Accession: NM_003378, NP_003369

UniProt: O15240

Pathways: Hormone Transport, Carbohydrate Homeostasis