Progesterone Receptor antibody (N-Term)

Catalog No. ABIN2777212

This Rabbit Polyclonal antibody specifically detects Progesterone Receptor in WB. It exhibits reactivity toward Human, Rat, Mouse, Pig, Rabbit, Goat and Saccharomyces cerevisiae.

Quick Overview for Progesterone Receptor antibody (N-Term) (ABIN2777212)

Target: Progesterone Receptor (PGR)

Reactivity: Human, Rat, Mouse, Pig, Rabbit, Goat, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Progesterone Receptor antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Progesterone Receptor Antibody

Binding Specificity: N-Term

Sequence: QAAAVEVEEE DGSESEESAG PLLKGKPRAL GGAAAGGGAA AVPPGAAAGG

Predicted Reactivity: Goat: 77%, Human: 93%, Mouse: 90%, Pig: 86%, Rabbit: 83%, Rat: 86%, Yeast: 85%

Characteristics: This is a rabbit polyclonal antibody against PGR. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human PGR

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Progesterone Receptor

Target: Progesterone Receptor (PGR)

Alternative Name: PGR

Background: PGR is a member of the steroid receptor superfamily. The protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy.
Alias Symbols: NR3C3, PR
Protein Interaction Partner: BCAS2, SRC, PGR, Dlg4, PARP1, ANP32A, XRCC5, PRKDC, XRCC6, MAGEA11, FKBP5, RBM23, RBM39, KAT2B, BRCA1, STUB1, DNAJC7, PPP5C, FKBP4, BPTF, CDK2, COPS5, NCOA1, UBC, ESR1, NCOA2, CCNA1, NCOA3, STAT3, SP1, Jdp2, Batf3, STAT5B, STAT5A, FGFR2, PRDM2, NCOR2, TAF
Protein Size: 769

Molecular Weight: 84 kDa

Gene ID: 5241

NCBI Accession: NM_001202474, NP_001189403

Pathways: Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Smooth Muscle Cell Migration