PQBP1 antibody (Middle Region)

Catalog No. ABIN2777308

The Rabbit Polyclonal anti-PQBP1 antibody is suitable to detect PQBP1 in samples from Human, Mouse, Rat, Cow, Dog, Horse, Guinea Pig, Pig and Rabbit. It has been validated for WB and IHC.

Quick Overview for PQBP1 antibody (Middle Region) (ABIN2777308)

Target: PQBP1 (Polyglutamine Binding Protein 1 (PQBP1))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Guinea Pig, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PQBP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-PQBP1 Antibody

Binding Specificity: Middle Region

Purpose: PQBP1 Antibody - middle region

Sequence: PSCGLPYYWN ADREEGKERR HHRREELAPY PKSKKAVSRK DEELDPMDPS

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 86%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against PQBP1. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PQBP1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP31454-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for PQBP1

Target: PQBP1 (Polyglutamine Binding Protein 1 (PQBP1))

Alternative Name: PQBP1

Background:

Background Information: This gene encodes a nuclear polyglutamine-binding protein that is involved with transcription activation. The encoded protein contains a WW domain. Mutations in this gene have been found in patients with Renpenning syndrome 1 and other syndromes with X-linked cognitive disability. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.

Gene Name: polyglutamine binding protein 1

Alternative Symbols: SHS, MRX2, MRX55, MRXS3, MRXS8, NPW38, RENS1

Protein Name: polyglutamine-binding protein 1

Molecular Weight: 30kDa

Gene ID: 10084

UniProt: O60828

Pathways: Ribonucleoprotein Complex Subunit Organization