ATF6 antibody (N-Term)

Catalog No. ABIN2777413

The Rabbit Polyclonal anti-ATF6 antibody (ABIN2777413) specifically detects ATF6 in WB. The antibody is reactive with Human, Rat, Rabbit, Cow, Dog, Horse and Guinea Pig samples.

Quick Overview for ATF6 antibody (N-Term) (ABIN2777413)

Target: ATF6 (Activating Transcription Factor 6 (ATF6))

Reactivity: Human, Rat, Rabbit, Cow, Dog, Horse, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATF6 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ATF6 Antibody

Binding Specificity: N-Term

Purpose: ATF6 Antibody - N-terminal region

Sequence: GYFTDTDELQ LEAANETYEN NFDNLDFDLD LMPWESDIWD INNQICTVKD

Predicted Reactivity: Cow: 86%, Dog: 79%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Rabbit: 92%, Rat: 79%

Characteristics: This is a rabbit polyclonal antibody against ATF6. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ATF6

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP31688-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for ATF6

Target: ATF6 (Activating Transcription Factor 6 (ATF6))

Alternative Name: ATF6

Background:

Background Information: ATF6 is an endoplasmic reticulum (ER) stress-regulated transmembrane transcription factor that activates the transcription of ER molecules.ATF6 is an endoplasmic reticulum (ER) stress-regulated transmembrane transcription factor that activates the transcription of ER molecules.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-171 AB015856.1 2-172 172-265 BC014969.1 124-217 266-336 AB015856.1 267-337 337-650 BC014969.1 289-602 651-1294 AF005887.1 626-1269 1295-2406 AB015856.1 1296-2407 2407-2488 AF005887.1 2375-2456

Gene Name: Activating transcription factor 6

Alternative Symbols: ACHM7, ATF6A

Protein Name: Cyclic AMP-dependent transcription factor ATF-6 alpha

Molecular Weight: 74kDa

Gene ID: 22926

NCBI Accession: NP_031374

UniProt: P18850

Pathways: ER-Nucleus Signaling, Unfolded Protein Response