GTF3C2 antibody (Middle Region)

Catalog No. ABIN2777493

The Rabbit Polyclonal anti-GTF3C2 antibody (ABIN2777493) specifically detects GTF3C2 in WB. The antibody is reactive with Human, Mouse, Dog, Horse, Rat, Cow, Guinea Pig and Rabbit samples.

Quick Overview for GTF3C2 antibody (Middle Region) (ABIN2777493)

Target: GTF3C2 (General Transcription Factor IIIC, Polypeptide 2, beta 110kDa (GTF3C2))

Reactivity: Human, Mouse, Dog, Horse, Rat, Cow, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GTF3C2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GTF3C2 Antibody

Binding Specificity: Middle Region

Purpose: GTF3C2 Antibody - middle region

Sequence: YKADLIPYQD SPEGPDHSSA SSGVPNPPKA RTYTETVNHH YLLFQDTDLG

Predicted Reactivity: Cow: 85%, Dog: 92%, Guinea Pig: 85%, Horse: 92%, Human: 100%, Mouse: 77%, Rabbit: 85%, Rat: 85%

Characteristics: This is a rabbit polyclonal antibody against GTF3C2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human GTF3C2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP31914-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for GTF3C2

Target: GTF3C2 (General Transcription Factor IIIC, Polypeptide 2, beta 110kDa (GTF3C2))

Alternative Name: GTF3C2

Background:

Background Information: GTF3C2 is required for RNA polymerase III-mediated transcription. GTF3C2 is a component of TFIIIC that initiates transcription complex assembly on tRNA and is required for transcription of 5S rRNA and other stable nuclear and cytoplasmic RNAs. GTF3C2 may play a direct role in stabilizing interactions of TFIIIC2 with TFIIIC1.

Gene Name: General transcription factor IIIC, polypeptide 2, beta 110 kDa

Alternative Symbols: TFIIIC110, TFIIIC-BETA

Protein Name: General transcription factor 3C polypeptide 2

Molecular Weight: 101kDa

Gene ID: 2976

NCBI Accession: NP_001512

UniProt: Q8WUA4