FOXA3 antibody (Forkhead Box A3) (Middle Region)

Details for Product anti-FOXA3 Antibody No. ABIN2777513, Supplier: Log in to see
Antigen
  • FOXA3
  • Zffkh1
  • fa11c04
  • fkd2
  • forkhead-2
  • wu:fa11c04
  • wu:fc37a08
  • zf-FKH1
  • FKHH3
  • HNF3G
  • TCF3G
  • HNF3-G
  • Hnf-3g
  • Hnf3g
  • Tcf-3g
  • Tcf3g
  • forkhead box A3
  • FOXA3
  • foxa3
  • Foxa3
Alternatives
anti-Cow (Bovine) FOXA3 antibody for Immunohistochemistry
Epitope
Middle Region
7
3
3
3
1
1
1
1
Reactivity
Cow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Rabbit, Rat (Rattus), Zebrafish (Danio rerio)
19
5
5
5
3
3
2
2
2
1
1
1
Host
Rabbit
13
7
Clonality
Polyclonal
Application
Immunohistochemistry (IHC), Western Blotting (WB)
15
5
3
2
2
1
1
1
Options
Supplier
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Immunogen The immunogen is a synthetic peptide directed towards the middle region of human FOXA3
Blocking Peptide Blocking peptide for this product available: ABIN976984
Sequence FENGCYLRRQ KRFKLEEKVK KGGSGAATTT RNGTGSAAST TTPAATVTSP
Predicted Reactivity Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 92%, Human: 100%, Mouse: 92%, Rabbit: 85%, Rat: 100%, Zebrafish: 79%
Characteristics This is a rabbit polyclonal antibody against FOXA3. It was validated on Western Blot and immunohistochemistry.
Purification Affinity Purified
Plasmids, Primers & others Plasmids, Primers & others FOXA3 products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name FOXA3 (FOXA3 Antibody Abstract)
Background FOXA3 encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. The crystal structure of a similar protein in rat has been resolved.
Alias Symbols: FKHH3, HNF3G, TCF3G
Protein Interaction Partner: PPARA, ALX4, TLE2, TLE1, HMGB1,
Protein Size: 350
Molecular Weight 37 kDa
Gene ID 3171
NCBI Accession NM_004497, NP_004488
UniProt P55318
Pathways Carbohydrate Homeostasis
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 350 AA

Restrictions For Research Use only
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Supplier Images
Western Blotting (WB) image for anti-Forkhead Box A3 (FOXA3) (Middle Region) antibody (ABIN2777513) WB Suggested Anti-FOXA3 Antibody Titration: 0.2-1 ug/ml Positive Control: Jurkat c...
Immunohistochemistry (IHC) image for anti-Forkhead Box A3 (FOXA3) (Middle Region) antibody (ABIN2777513) Human Lung
Product cited in: Menga, Infantino, Iacobazzi, Convertini, Palmieri, Iacobazzi: "Insight into mechanism of in vitro insulin secretion increase induced by antipsychotic clozapine: role of FOXA1 and mitochondrial citrate carrier." in: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, Vol. 23, Issue 8, pp. 978-87, 2013 (PubMed).

Background publications Kaestner: "The hepatocyte nuclear factor 3 (HNF3 or FOXA) family in metabolism." in: Trends in endocrinology and metabolism: TEM, Vol. 11, Issue 7, pp. 281-5, 2001 (PubMed).

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