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PAWR antibody (Middle Region)

The Rabbit Polyclonal anti-PAWR antibody has been validated for WB and IHC. It is suitable to detect PAWR in samples from Human, Mouse, Rat, Dog, Horse and Rabbit.
Catalog No. ABIN2777555

Quick Overview for PAWR antibody (Middle Region) (ABIN2777555)

Target

See all PAWR Antibodies
PAWR (PRKC, Apoptosis, WT1, Regulator (PAWR))

Reactivity

  • 33
  • 20
  • 20
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
Human, Mouse, Rat, Dog, Horse, Rabbit

Host

  • 33
  • 1
Rabbit

Clonality

  • 32
  • 2
Polyclonal

Conjugate

  • 20
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
This PAWR antibody is un-conjugated

Application

  • 19
  • 13
  • 8
  • 5
  • 4
  • 4
  • 2
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • Binding Specificity

    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region

    Sequence

    SYLLQEPPRT VSGRYKSTTS VSEEDVSSRY SRTDRSGFPR YNRDANVSGT

    Predicted Reactivity

    Dog: 100%, Horse: 85%, Human: 100%, Mouse: 91%, Rabbit: 77%, Rat: 91%

    Characteristics

    This is a rabbit polyclonal antibody against PAWR. It was validated on Western Blot and immunohistochemistry.

    Purification

    Protein A purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the middle region of human PAWR
  • Application Notes

    Optimal working dilutions should be determined experimentally by the investigator.

    Comment

    Antigen size: 340 AA

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handling Advice

    Avoid repeated freeze-thaw cycles.

    Storage

    -20 °C

    Storage Comment

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target

    PAWR (PRKC, Apoptosis, WT1, Regulator (PAWR))

    Alternative Name

    PAWR

    Background

    The tumor suppressor WT1 represses and activates transcription. Anti-Prostate Apoptosis Response Protein Par-4 (PAWR) is a WT1-interacting protein that itself functions as a transcriptional repressor. It contains a putative leucine zipper domain which interacts with the zinc finger DNA binding domain of WT1. This protein is specifically upregulated during apoptosis of prostate cells.
    Alias Symbols: PAR4, Par-4
    Protein Interaction Partner: FBXO45, UBC, EED, FAM129B, SNX6, CAND1, VPS29, JMJD6, STAT1, SNX2, SHMT2, SHMT1, PPM1G, IDE, H3F3A, CARS, ATP6V1C1, APEH, PAN2, DRD2, DAPK3, SQSTM1, PRKCZ, Spsb4, Spsb2, SPSB1, FBXO25, HSPA5, Cep350, Kif23, THAP1, SLC5A7, AATF, TFPT, PAWR, WT1, RRAS2, ATP
    Protein Size: 340

    Molecular Weight

    37 kDa

    Gene ID

    5074

    NCBI Accession

    NM_002583, NP_002574

    UniProt

    O75796
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