PIAS3 antibody (C-Term)

Catalog No. ABIN2777574

Product Details anti-PIAS3 Antibody

Target: PIAS3 (Protein Inhibitor of Activated STAT, 3 (PIAS3))

Binding Specificity: C-Term

Reactivity: Human, Rat, Mouse, Dog, Cow, Pig, Horse, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PIAS3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: TSLDEQDALG HFFQYRGTPS HFLGPLAPTL GSSHCSATPA PPPGRVSSIV

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against PIAS3. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human PIAS3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 619 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PIAS3

Target: PIAS3 (Protein Inhibitor of Activated STAT, 3 (PIAS3))

Alternative Name: PIAS3 (PIAS3 Products)

Synonyms: PIAS3 antibody, Pias3l antibody, ZMIZ5 antibody, protein inhibitor of activated STAT 3 antibody, protein inhibitor of activated STAT, 3 antibody, protein inhibitor of activated STAT 3 L homeolog antibody, PIAS3 antibody, pias3 antibody, Pias3 antibody, pias3.L antibody

Background: PIAS3 is a member of the protein inhibitor of activated STAT (PIAS) family. It also activates TGF-beta/SMAD transcriptional responses.
Alias Symbols: ZMIZ5
Protein Interaction Partner: UBC, HIC1, TRIM63, TRIM55, TAB2, SUMO1, CBS, SUMO2, SUMO3, STAT3, NCOA2, CREM, PRPF40A, SERPINA10, GEMIN4, UBE2I, SKIL, HNRNPK, ZFHX3, SERBP1, SATB1, ERBB4, Bcl11a, ELAVL1, PPP1CA, Grm7, Grm8, Grm6, Grm4, TRIM8, RAC1, C19orf60, CARHSP1, UBA1, PSMC1, TRIM2
Protein Size: 619

Molecular Weight: 67 kDa

Gene ID: 10401

NCBI Accession: NM_006099, NP_006090

UniProt: Q9Y6X2

Pathways: JAK-STAT Signaling