RBAK antibody (Middle Region)

Catalog No. ABIN2777685

The Rabbit Polyclonal anti-RBAK antibody (ABIN2777685) specifically detects RBAK in WB and IHC. The antibody is reactive with Human, Mouse, Rat, Guinea Pig, Horse, Cow, Dog and Rabbit samples.

Quick Overview for RBAK antibody (Middle Region) (ABIN2777685)

Target: RBAK (RB-Associated KRAB Zinc Finger (RBAK))

Reactivity: Human, Mouse, Rat, Guinea Pig, Horse, Cow, Dog, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RBAK antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-RBAK Antibody

Binding Specificity: Middle Region

Purpose: RBAK Antibody - middle region

Sequence: HYRSHLEEKP YECNECGKTF NLNSAFIRHR KVHTEEKSHE CSECGKFSQL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 79%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against RBAK. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human RBAK

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8110121

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for RBAK

Target: RBAK (RB-Associated KRAB Zinc Finger (RBAK))

Alternative Name: RBAK

Background:

Background Information: RBAK encodes a nuclear protein which interacts with the tumor suppressor retinoblastoma 1. The two interacting proteins are thought to act as a transcriptional repressor for promoters which are activated by the E2F1 transcription factor. This protein contains a Kruppel-associated box (KRAB), which is a transcriptional repressor motif.This gene encodes a nuclear protein which interacts with the tumor suppressor retinoblastoma 1. The two interacting proteins are thought to act as a transcriptional repressor for promoters which are activated by the E2F1 transcription factor. This protein contains a Kruppel-associated box (KRAB), which is a transcriptional repressor motif.

Gene Name: RB-associated KRAB zinc finger

Alternative Symbols: ZNF769

Protein Name: RB-associated KRAB zinc finger protein

Molecular Weight: 83kDa

Gene ID: 57786

NCBI Accession: NP_066986

UniProt: Q9NYW8