KDM3B antibody (N-Term)

Catalog No. ABIN2777712

This Rabbit Polyclonal antibody specifically detects KDM3B in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Cow, Horse, Rabbit and Guinea Pig.

Quick Overview for KDM3B antibody (N-Term) (ABIN2777712)

Target: KDM3B (Lysine (K)-Specific Demethylase 3B (KDM3B))

Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KDM3B antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-KDM3B Antibody

Binding Specificity: N-Term

Sequence: KESHSPFGLD SFNSTAKVSP LTPKLFNSLL LGPTASNNKT EGSSLRDLLH

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against KDM3B. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human KDM3B

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for KDM3B

Target: KDM3B (Lysine (K)-Specific Demethylase 3B (KDM3B))

Alternative Name: KDM3B

Background: KDM3B is a histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. It may have tumor suppressor activity.
Protein Interaction Partner: UBC, WWOX, SPAG8, NCS1, SRP68, ZNF512B, VCP, HIST3H3, CREBBP, ELAVL1, SUMO2, ESRRA, USP18,
Protein Size: 759

Molecular Weight: 83 kDa

Gene ID: 51780

Pathways: Warburg Effect