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KDM3B antibody (N-Term)

KDM3B Reactivity: Human WB Host: Rabbit Polyclonal RB10782 unconjugated
Catalog No. ABIN387870
  • Target See all KDM3B Antibodies
    KDM3B (Lysine (K)-Specific Demethylase 3B (KDM3B))
    Binding Specificity
    • 15
    • 9
    • 8
    • 7
    • 7
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 25-57, N-Term
    Reactivity
    • 59
    • 30
    • 22
    • 6
    • 5
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 59
    • 3
    Rabbit
    Clonality
    • 60
    • 2
    Polyclonal
    Conjugate
    • 33
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This KDM3B antibody is un-conjugated
    Application
    • 54
    • 29
    • 13
    • 13
    • 7
    • 7
    • 7
    • 5
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB)
    Predicted Reactivity
    M
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This JMJD1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 25-57 amino acids from the N-terminal region of human JMJD1B.
    Clone
    RB10782
    Isotype
    Ig Fraction
    Top Product
    Discover our top product KDM3B Primary Antibody
  • Application Notes
    WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Target
    KDM3B (Lysine (K)-Specific Demethylase 3B (KDM3B))
    Alternative Name
    JMJD1B (KDM3B Products)
    Background
    Covalent modification of histones plays critical role in regulating chromatin structure and transcription. While most covalent histone modifications are reversible, only recently has it been established that methyl groups are subject to enzymatic removal from histones. A family of novel JmjC domain-containing histone demethylation (JHDM) enzymes have been identified that perform this specific function. Histone demethylation by JHDM proteins requires cofactors Fe(II) and alpha-ketoglutarate. Family members include JHDM1 (demethylating histone 3 at lysine 36), and JHDM2A as well as JMJD2CH3K9 (both of which demethylate histone 3 at lysine 9). Contributions of histone demethylase activity to tumor development, decreases in cell proliferation, and hormone-dependent transcriptional activation have been observed.
    Molecular Weight
    191581
    Gene ID
    51780
    NCBI Accession
    NP_057688
    UniProt
    Q7LBC6
    Pathways
    Warburg Effect
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