KDM3B antibody (Internal Region)

Catalog No. ABIN6258864

The Rabbit Polyclonal anti-KDM3B antibody is suitable to detect KDM3B in samples from Human and Mouse. It has been validated for WB, IHC, IF and ICC.

Quick Overview for KDM3B antibody (Internal Region) (ABIN6258864)

Target: KDM3B (Lysine (K)-Specific Demethylase 3B (KDM3B))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KDM3B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Product Details anti-KDM3B Antibody

Binding Specificity: Internal Region

Purpose: JMJD1B Antibody

Specificity: JMJD1B Antibody detects endogenous levels of total JMJD1B.

Predicted Reactivity: Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human JMJD1B, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:200,WB 1:500-1:2000, IF/ICC 1:100-1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for KDM3B

Target: KDM3B (Lysine (K)-Specific Demethylase 3B (KDM3B))

Alternative Name: JMJD1B

Background:

Description: Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May have tumor suppressor activity.

Gene: KDM3B

Molecular Weight: 240 kDa

Gene ID: 51780

UniProt: Q7LBC6

Pathways: Warburg Effect