POU3F3 antibody (N-Term)

Catalog No. ABIN2777730

Product Details anti-POU3F3 Antibody

Target: POU3F3 (POU Class 3 Homeobox 3 (POU3F3))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POU3F3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: GGGGGGGGGA GGGGGGMQPG SAAVTSGAYR GDPSSVKMVQ SDFMQGAMAA

Predicted Reactivity: Human: 100%, Mouse: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against POU3F3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human POU3F3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 500 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for POU3F3

Target: POU3F3 (POU Class 3 Homeobox 3 (POU3F3))

Alternative Name: POU3F3 (POU3F3 Products)

Synonyms: BRN1 antibody, OTF8 antibody, Brn1 antibody, RHS1 antibody, Brn-1 antibody, Otf8 antibody, Skin1 antibody, brn1 antibody, nrl-20 antibody, nrl20-A antibody, pou1 antibody, pou23 antibody, wu:fb92g06 antibody, zfpou1 antibody, zp23 antibody, zp23pou antibody, BRN-1.1 antibody, ZP12POU antibody, brn1.1 antibody, pou12 antibody, wu:fc33a11 antibody, zp12 antibody, POU class 3 homeobox 3 antibody, POU domain, class 3, transcription factor 3 antibody, POU class 3 homeobox 3 S homeolog antibody, POU class 3 homeobox 3b antibody, POU class 3 homeobox 3a antibody, POU3F3 antibody, Pou3f3 antibody, pou3f3.S antibody, pou3f3b antibody, pou3f3a antibody

Background: POU3F3 is the transcription factor that acts synergistically with SOX11 and SOX4. POU3F3 plays a role in neuronal development. POU3F3 is implicated in an enhancer activity at the embryonic met-mesencephalic junction, the enhancer element contains the octamer motif (5'-ATTTGCAT-3').POU3F3 is a member of the class III POU family of transcription factors (see POU3F1, MIM 602479) that are expressed in the central nervous system. The POU domain in these proteins is required for high affinity binding to octamer DNA sequences Sumiyama et al. (1996) [PubMed 8703082].[supplied by OMIM].
Alias Symbols: BRN1, OTF8
Protein Interaction Partner: Dlg4, SOX8, PPP1R15A, SOX10, SOX11, POU3F4,
Protein Size: 500

Molecular Weight: 50 kDa

Gene ID: 5455

NCBI Accession: NM_006236, NP_006227

UniProt: P20264