IVNS1ABP antibody (Influenza Virus NS1A Binding Protein) (N-Term)

Details for Product anti-IVNS1ABP Antibody No. ABIN2777748
Target
Binding Specificity
N-Term
3
1
1
1
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat, Zebrafish (Danio rerio)
9
5
3
3
3
3
2
2
2
2
1
1
1
1
1
Host
Rabbit
9
1
Clonality
Polyclonal
Application
Immunohistochemistry (IHC), Western Blotting (WB)
10
6
4
3
1
Options
Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human IVNS1ABP
Blocking Peptide Blocking peptide for this product available: ABIN978677
Sequence RAVLACCSPY LFEIFNSDSD PHGISHVKFD DLNPEAVEVL LNYAYTAQLK
Predicted Reactivity Cow: 86%, Dog: 100%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 92%, Pig: 100%, Rabbit: 93%, Rat: 93%, Zebrafish: 86%
Characteristics This is a rabbit polyclonal antibody against IVNS1ABP. It was validated on Western Blot and immunohistochemistry.
Purification Affinity Purified
Target
Alternative Name IVNS1ABP (IVNS1ABP Antibody Abstract)
Background This gene encodes a protein which interacts with the nonstructural NS1 protein of the influenza A virus. In noninfected cells, affinity-purified antibodies localized this protein in nuclear regions enriched with the spliceosome assembly factor SC35, suggesting an association with the cellular splicing apparatus. In influenza A virus-infected cells, the protein relocalized throughout the nucleoplasm and appeared distinct from the SC35 domains, which suggests that its function may be disturbed or altered.
Alias Symbols: ND1, NS-1, NS1BP, FLARA3, KLHL39, NS1-BP, HSPC068
Protein Interaction Partner: UBC, DHX36, PARP1, ACTB, ZC3HAV1, RBMX, LARP1, DHX30, HNRNPUL1, IGF2BP1, IVNS1ABP, DDX17, HNRNPR, LRPPRC, THRAP3, G3BP2, DDX21, PABPC4, GBF1, STAU1, UPF1, POLR2A, YBX1, NCBP1, HNRNPM, MYH9, ILF3, ILF2, HSP90AB1, HSPA8, HNRNPU, HNRNPL, HNRNPK, HNRNPF, HNRN
Protein Size: 642
Molecular Weight 72 kDa
Gene ID 10625
NCBI Accession NM_006469, NP_006460
UniProt Q9Y6Y0
Pathways Negative Regulation of intrinsic apoptotic Signaling
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 642 AA

Restrictions For Research Use only
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Images
Image no. 1 for anti-Influenza Virus NS1A Binding Protein (IVNS1ABP) (N-Term) antibody (ABIN2777748) WB Suggested Anti-IVNS1ABP Antibody Titration: 0.2-1 ug/ml Positive Control: K562 ...
Image no. 2 for anti-Influenza Virus NS1A Binding Protein (IVNS1ABP) (N-Term) antibody (ABIN2777748) Human Liver