This gene encodes a protein which interacts with the nonstructural NS1 protein of the influenza A virus. In noninfected cells, affinity-purified antibodies localized this protein in nuclear regions enriched with the spliceosome assembly factor SC35, suggesting an association with the cellular splicing apparatus. In influenza A virus-infected cells, the protein relocalized throughout the nucleoplasm and appeared distinct from the SC35 domains, which suggests that its function may be disturbed or altered.
Alias Symbols: ND1, NS-1, NS1BP, FLARA3, KLHL39, NS1-BP, HSPC068
Protein Interaction Partner: UBC, DHX36, PARP1, ACTB, ZC3HAV1, RBMX, LARP1, DHX30, HNRNPUL1, IGF2BP1, IVNS1ABP, DDX17, HNRNPR, LRPPRC, THRAP3, G3BP2, DDX21, PABPC4, GBF1, STAU1, UPF1, POLR2A, YBX1, NCBP1, HNRNPM, MYH9, ILF3, ILF2, HSP90AB1, HSPA8, HNRNPU, HNRNPL, HNRNPK, HNRNPF, HNRN
Protein Size: 642