RING1 antibody (Middle Region)

Catalog No. ABIN487035

The Rabbit Polyclonal anti-RING1 antibody (ABIN487035) specifically detects RING1 in WB and IHC. The antibody is reactive with Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse and Rabbit samples.

Quick Overview for RING1 antibody (Middle Region) (ABIN487035)

Target: RING1 (Ring Finger Protein 1 (RING1))

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RING1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-RING1 Antibody

Binding Specificity: Middle Region

Sequence: TGGGGTGGVG GGAGSEDSGD RGGTLGGGTL GPPSPPGAPS PPEPGGEIEL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against RING1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human RING1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 406 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for RING1

Target: RING1 (Ring Finger Protein 1 (RING1))

Alternative Name: RING1

Background: RING1 belongs to the RING finger family, members of which characterized by a RING domain, a zinc-binding motif related to the zinc finger domain. The protein can bind DNA and can act as a transcriptional repressor. It is associated with the multimeric pol
Alias Symbols: RNF1, RING1A
Protein Interaction Partner: CBX8, RYBP, YAF2, BMI1, UBC, SNAI1, EED, RNF2, HECW2, CSNK2A2, YY1, FBXO38, CBX7, CBX6, FHL1, TP53, NOTCH1, APP, PCGF1, PCGF5, PCGF6, PCGF3, PCGF2, CBX2, PHC3, WDR5, CBX4, PHC2, PHC1, YY2, ZFP42, SMARCAD1, PIK3R3, TOP2A, TERF2, TERF1, USP11, USP7, CENPA,
Protein Size: 406

Molecular Weight: 42 kDa

Gene ID: 6015

NCBI Accession: NM_002931, NP_002922

UniProt: Q06587