T-Box 19 antibody (N-Term)

Catalog No. ABIN2777906

This Rabbit Polyclonal antibody specifically detects T-Box 19 in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Cow, Guinea Pig and Rabbit.

Quick Overview for T-Box 19 antibody (N-Term) (ABIN2777906)

Target: T-Box 19 (TBX19)

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This T-Box 19 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-T-Box 19 Antibody

Binding Specificity: N-Term

Purpose: TBXT Antibody - N-terminal region

Sequence: SSPGTESAGK SLQYRVDHLL SAVENELQAG SEKGDPTERE LRVGLEESEL

Predicted Reactivity: Cow: 100%, Dog: 92%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 92%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against T. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human T

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP33389-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for T-Box 19

Target: T-Box 19 (TBX19)

Alternative Name: TBXT

Background:

Background Information: The protein encoded by this gene is an embryonic nuclear transcription factor that binds to a specific DNA element, the palindromic T-site. It binds through a region in its N-terminus, called the T-box, and effects transcription of genes required for mesoderm formation and differentiation. The protein is localized to notochord-derived cells. Two transcript variants encoding different isoforms have been found for this gene.

Gene Name: T-box transcription factor T

Alternative Symbols: T, TFT, SAVA

Protein Name: T-box transcription factor T, brachyury protein

Molecular Weight: 47kDa

Gene ID: 6862

NCBI Accession: NP_003172

UniProt: O15178