APOBEC3G antibody (N-Term)
Quick Overview for APOBEC3G antibody (N-Term) (ABIN2777995)
Target
See all APOBEC3G AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- N-Term
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Sequence
- AKIFRGQVYS ELKYHPEMRF FHWFSKWRKL HRDQEYEVTW YISWSPCTKC
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Predicted Reactivity
- Human: 100%, Pig: 79%
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Characteristics
- This is a rabbit polyclonal antibody against APOBEC3G. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Protein A purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human APOBEC3G
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
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Comment
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Antigen size: 384 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Interferon-alpha induces high expression of APOBEC3G and STAT-1 in vitro and in vivo." in: International journal of molecular sciences, Vol. 11, Issue 9, pp. 3501-12, (2010) (PubMed).
: "
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Interferon-alpha induces high expression of APOBEC3G and STAT-1 in vitro and in vivo." in: International journal of molecular sciences, Vol. 11, Issue 9, pp. 3501-12, (2010) (PubMed).
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- APOBEC3G (Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3G (APOBEC3G))
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Alternative Name
- APOBEC3G
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Background
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Anti-APOBEC3G is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control. The protein encoded by this gene has been found to be a specific inhibitor of human immunodeficiency virus-1 (HIV-1) infectivity.
Alias Symbols: ARCD, ARP9, ARP-9, CEM15, CEM-15, MDS019, bK150C2.7, dJ494G10.1
Protein Interaction Partner: vpr, vif, UNG1, APP, UBC, CBFB, APOBEC3G, HSPA4, gag, PTN, PRKACA, UBA52,
Protein Size: 384 -
Molecular Weight
- 46 kDa
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Gene ID
- 60489
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NCBI Accession
- NM_021822, NP_068594
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UniProt
- Q9HC16
Target
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