Claudin 23 antibody (C-Term)

Catalog No. ABIN2778051

This anti-Claudin 23 antibody is a Rabbit Polyclonal antibody detecting Claudin 23 in WB and IHC. Suitable for Human, Mouse, Rat, Pig and Saccharomyces cerevisiae.

Quick Overview for Claudin 23 antibody (C-Term) (ABIN2778051)

Target: Claudin 23 (CLDN23)

Reactivity: Human, Mouse, Rat, Pig, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Claudin 23 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-Claudin 23 Antibody

Binding Specificity: C-Term

Sequence: IKYYSDGQHR PPPAQHRKPK PKPKVGFPMP RPRPKAYTNS VDVLDGEGWE

Predicted Reactivity: Human: 100%, Mouse: 86%, Pig: 91%, Rat: 85%, Yeast: 82%

Characteristics: This is a rabbit polyclonal antibody against CLDN23. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CLDN23

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 167 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Claudin 23

Target: Claudin 23 (CLDN23)

Alternative Name: CLDN23

Background: CLDN23 is a four-transmembrane protein with WWCC motif, defined by W-X(17-22)-W-X(2)-C-X(8-10)-C. It is a candidate tumor suppressor gene implicated in intestinal-type gastric cancer.
Alias Symbols: CLDNL, hCG1646163
Protein Size: 167

Molecular Weight: 17 kDa

Gene ID: 137075

NCBI Accession: NM_194284, NP_919260

UniProt: Q6ZW63

Pathways: Cell-Cell Junction Organization, Hepatitis C