KCNJ5 antibody (Middle Region)

Catalog No. ABIN2778095

This Rabbit Polyclonal antibody specifically detects KCNJ5 in WB. It exhibits reactivity toward Human, Rat, Mouse, Cow, Rabbit, Horse, Guinea Pig and Zebrafish (Danio rerio).

Quick Overview for KCNJ5 antibody (Middle Region) (ABIN2778095)

Target: KCNJ5 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 5 (KCNJ5))

Reactivity: Human, Rat, Mouse, Cow, Rabbit, Horse, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KCNJ5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-KCNJ5 Antibody

Binding Specificity: Middle Region

Sequence: SGFALKRNVL GRNLTANDPS QEYVASEGEE DPEVEFLKSL TTKQKQKLLR

Predicted Reactivity: Cow: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against CIR. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CIR

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 324 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for KCNJ5

Target: KCNJ5 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 5 (KCNJ5))

Alternative Name: CIR

Background: CIR may modulate splice site selection during alternative splicing of pre-mRNAs. CIR regulates transcription and acts as corepressor for RBPSUH by recruiting RBPSUH to the Sin3-histone deacetylase complex (HDAC). CIR is also required for RBPSUH-mediated repression of transcription.
Alias Symbols: CIR
Protein Interaction Partner: CEP76, NEK6, U2AF1, SRSF2, SRSF1, RP9, HDAC2, SAP30, SNW1, TCEA1, NCOR2, RBPJ,
Protein Size: 324

Molecular Weight: 34 kDa

Gene ID: 9541

UniProt: Q86X95

Pathways: Notch Signaling