Cnpase antibody (Middle Region)

Catalog No. ABIN2778174

The Rabbit Polyclonal anti-Cnpase antibody is suitable to detect Cnpase in samples from Human, Mouse, Rat, Dog, Pig, Rabbit and Horse. It has been validated for WB and IHC.

Quick Overview for Cnpase antibody (Middle Region) (ABIN2778174)

Target: Cnpase (CNP) (2',3'-Cyclic Nucleotide 3' phosphodiesterase (CNP))

Reactivity: Human, Mouse, Rat, Dog, Pig, Rabbit, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cnpase antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-Cnpase Antibody

Binding Specificity: Middle Region

Purpose: CNP Antibody - middle region

Sequence: LYSLGNGRWM LTLAKNMEVR AIFTGYYGKG KPVPTQGSRK GGALQSCTII

Predicted Reactivity: Dog: 93%, Horse: 93%, Human: 100%, Mouse: 86%, Pig: 79%, Rabbit: 93%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against CNP. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CNP

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP33879-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for Cnpase

Target: Cnpase (CNP) (2',3'-Cyclic Nucleotide 3' phosphodiesterase (CNP))

Alternative Name: CNP

Background:

Background Information: CNP belongs to the cyclic nucleotide phosphodiesterase family. It interacts with tubulin and promotes microtubule assembly for process outgrowth in oligodendrocytes. reduced CNP expression in the schizophrenic brain is relevant to disease etiology and therefore provide support for the general hypothesis that altered oligodendrocyte function is an etiological factor in schizophrenia.

Gene Name: 2',3'-cyclic nucleotide 3' phosphodiesterase

Alternative Symbols: CNP1, HLD20

Protein Name: 2',3'-cyclic-nucleotide 3'-phosphodiesterase

Molecular Weight: 47kDa

Gene ID: 1267

NCBI Accession: NP_149124

UniProt: P09543