RGS6 antibody (N-Term)

Catalog No. ABIN2778234

The Rabbit Polyclonal anti-RGS6 antibody (ABIN2778234) specifically detects RGS6 in WB. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for RGS6 antibody (N-Term) (ABIN2778234)

Target: RGS6 (Regulator of G-Protein Signaling 6 (RGS6))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RGS6 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RGS6 Antibody

Binding Specificity: N-Term

Purpose: RGS6 Antibody - N-terminal region

Sequence: AQGSGDQRAV GVADPEESSP NMIVYCKIED IITKMQDDKT GGVPIRTVKS

Predicted Reactivity: Human: 100%, Mouse: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against RGS6. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human RGS6

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP34042-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for RGS6

Target: RGS6 (Regulator of G-Protein Signaling 6 (RGS6))

Alternative Name: RGS6

Background:

Background Information: Members of the RGS (regulator of G protein signaling) family, such as RGS6, modulate G protein function by activating the intrinsic GTPase activity of the alpha (guanine nucleotide-binding) subunits.Members of the RGS (regulator of G protein signaling) family have been shown to modulate the functioning of G proteins by activating the intrinsic GTPase activity of the alpha (guanine nucleotide-binding) subunits.[supplied by OMIM].

Gene Name: Regulator of G-protein signaling 6

Alternative Symbols: GAP, S914, HA117

Protein Name: Regulator of G-protein signaling 6

Molecular Weight: 54kDa

Gene ID: 9628

NCBI Accession: NP_004287

UniProt: P49758

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling