RGS20 antibody (N-Term)

Catalog No. ABIN2778241

The Rabbit Polyclonal anti-RGS20 antibody (ABIN2778241) specifically detects RGS20 in WB. The antibody is reactive with Human, Mouse, Rat, Guinea Pig and Horse samples.

Quick Overview for RGS20 antibody (N-Term) (ABIN2778241)

Target: RGS20 (Regulator of G-Protein Signaling 20 (RGS20))

Reactivity: Human, Mouse, Rat, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RGS20 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RGS20 Antibody

Binding Specificity: N-Term

Purpose: RGS20 Antibody - N-terminal region

Sequence: NACCFCWCCC CSCSCLTVRN QEDQRPTIAS HELRADLPTW EESPAPTLEE

Specificity: 100 % homologous to isoforms 1, 2, 4-6.

Predicted Reactivity: Guinea Pig: 79%, Horse: 79%, Human: 100%, Mouse: 85%, Rat: 79%

Characteristics: This is a rabbit polyclonal antibody against RGS20. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP34052-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for RGS20

Target: RGS20 (Regulator of G-Protein Signaling 20 (RGS20))

Alternative Name: RGS20

Background:

Background Information: The protein encoded by this gene belongs to the family of regulator of G protein signaling (RGS) proteins, which are regulatory and structural components of G protein-coupled receptor complexes. RGS proteins inhibit signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound forms. This protein selectively binds to G(z)-alpha and G(alpha)-i2 subunits, and regulates their signaling activities. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene Name: Regulator of G-protein signaling 20

Alternative Symbols: RGSZ1, ZGAP1, gz-GAP, g(z)GAP

Protein Name: Regulator of G-protein signaling 20

Molecular Weight: 27kDa

Gene ID: 8601

NCBI Accession: NP_003693

UniProt: O76081

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling