RGS20 antibody (N-Term)

Catalog No. ABIN2778243

Product Details anti-RGS20 Antibody

Target: RGS20 (Regulator of G-Protein Signaling 20 (RGS20))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RGS20 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: KHFSRPSIWT QFLPLFRAQR YNTDIHQITE NEGDLRAVPD IKSFPPAQLP

Specificity: 100 % homologous to isoforms 1 (31kD) and 6 (44kD).

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against RGS20. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human RGS20

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 388 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for RGS20

Target: RGS20 (Regulator of G-Protein Signaling 20 (RGS20))

Alternative Name: RGS20 (RGS20 Products)

Background: Regulator of G protein signaling (RGS) proteins are regulatory and structural components of G protein-coupled receptor complexes. RGS proteins are GTPase-activating proteins for Gi and Gq class G-alpha proteins. They accelerate transit through the cycle of GTP binding and hydrolysis and thereby accelerate signaling kinetics and termination.
Alias Symbols: RGSZ1, ZGAP1
Protein Interaction Partner: KRTAP5-6, LCE3E, LCE2D, LCE2A, LCE1B, KLHL38, LCE4A, TBC1D16, CATSPER1, PTPMT1, KRTAP4-2, CRCT1, PVRL3, MAPKBP1, GLRX3, CREB5, PTGER3, OTX1, KRTAP5-9, INS, HSPD1, HOXA1, GNAI2, AQP1, FASLG, KIF1A, ADRB2, OSTM1, STMN2, GNAI3, GNAI1, GNAZ, UBC, GNAO1, TXLNA
Protein Size: 388

Molecular Weight: 44 kDa

Gene ID: 8601

NCBI Accession: NM_170587, NP_733466

UniProt: O76081

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling