NPM1 antibody (C-Term)

Catalog No. ABIN2778268

This Rabbit Polyclonal antibody specifically detects NPM1 in WB and IHC. It exhibits reactivity toward Human and Mouse.

Quick Overview for NPM1 antibody (C-Term) (ABIN2778268)

Target: NPM1 (Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) (NPM1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NPM1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-NPM1 Antibody

Binding Specificity: C-Term

Sequence: DDDFDDEEAE EKAPVKKGQE SFKKQEKTPK TPKGPSSVED IKAKMQASIE

Predicted Reactivity: Human: 100%, Mouse: 92%

Characteristics: This is a rabbit polyclonal antibody against NPM1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human NPM1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 265 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for NPM1

Target: NPM1 (Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) (NPM1))

Alternative Name: NPM1

Background: NPM3 is a member of Nucleophosmin (NPM) family. NPM is a ubiquitously expressed nucleolar phosphoprotein that continuously shuttles between the nucleus and cytoplasm
Alias Symbols: B23, NPM
Protein Interaction Partner: COX8A, NPM2, HUWE1, UBC, PA2G4, FUS, TP53, AURKA, SUMO2, SUMO3, ELF4, STAU1, CDKN2A, LGR4, SUMO1, MDM2, RPA3, RPA2, RPA1, ERG, rev, TRMT61A, OSBP, KPNA1, LIMCH1, ARMCX3, YWHAQ, PARK2, TARDBP, TUBA1C, TAB2, CEP152, DZIP1, COPG1, STK38, COPE, PARK7, AKAP11,
Protein Size: 265

Molecular Weight: 29 kDa

Gene ID: 4869

NCBI Accession: NM_199185, NP_954654

UniProt: P06748

Pathways: Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly