MAZ antibody (Middle Region)
Quick Overview for MAZ antibody (Middle Region) (ABIN2778296)
Target
See all MAZ AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- Middle Region
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Sequence
- ALEKKTKSKG PYICALCAKE FKNGYNLRRH EAIHTGAKAG RVPSGAMKMP
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Predicted Reactivity
- Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
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Characteristics
- This is a rabbit polyclonal antibody against MAZ. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human MAZ
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
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Comment
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Antigen size: 477 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- MAZ (MYC-Associated Zinc Finger Protein (Purine-Binding Transcription Factor) (MAZ))
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Alternative Name
- MAZ
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Background
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MAZ may function as a transcription factor with dual roles in transcription initiation and termination.It binds to two sites, ME1a1 and ME1a2, within the c-myc promoter having greater affinity for the former. It also binds to multiple G/C-rich sites within the promoter of the Sp1 family of transcription factors.
Alias Symbols: PUR1, Pur-1, SAF-1, SAF-2, ZF87, ZNF801, Zif87, SAF-3
Protein Interaction Partner: HECW2, MAPK14, BPTF, JUN, FOS, KEAP1, DCC, CSNK2A1,
Protein Size: 477 -
Molecular Weight
- 48 kDa
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Gene ID
- 4150
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NCBI Accession
- NM_002383, NP_002374
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UniProt
- P56270
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Pathways
- Chromatin Binding
Target
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