MYC-Associated Zinc Finger Protein (Purine-Binding Transcription Factor) (MAZ) (N-Term) antibody

Details for Product No. ABIN2780422, Supplier: Log in to see
Antigen
  • PUR1
  • Pur-1
  • SAF-1
  • SAF-2
  • SAF-3
  • ZF87
  • ZNF801
  • Zif87
  • MYC associated zinc finger protein
  • MYC-associated zinc finger protein (purine-binding transcription factor)
  • myc-associated zinc finger protein (purine-binding transcription factor) L homeolog
  • MAZ
  • Maz
  • maz.L
Alternatives
anti-Human MYC-Associated Zinc Finger Protein (Purine-Binding Transcription Factor) antibody for Immunohistochemistry
Epitope
N-Term
8
6
6
4
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Pig (Porcine), Rat (Rattus)
74
37
37
6
5
4
3
2
1
1
1
Host
Rabbit
56
18
Clonality
Polyclonal
Conjugate
Un-conjugated
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (IHC), Western Blotting (WB)
52
28
13
10
7
6
3
3
2
2
2
Options
Supplier
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Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human MAZ
Blocking Peptide Blocking peptide for this product available: ABIN979860
Sequence FPVFPCTLLA PPFPVLGLDS RGVGGLMNSF PPPQGHAQNP LQVGAELQSR
Predicted Reactivity Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%
Characteristics This is a rabbit polyclonal antibody against MAZ. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Antigen
Alternative Name MAZ (MAZ Antibody Abstract)
Background MAZ may function as a transcription factor with dual roles in transcription initiation and termination.It binds to two sites, ME1a1 and ME1a2, within the c-myc promoter having greater affinity for the former. It also binds to multiple G/C-rich sites within the promoter of the Sp1 family of transcription factors.
Alias Symbols: PUR1, Pur-1, SAF-1, SAF-2, ZF87, ZNF801, Zif87, SAF-3
Protein Interaction Partner: HECW2, MAPK14, BPTF, JUN, FOS, KEAP1, DCC, CSNK2A1,
Protein Size: 477
Molecular Weight 48 kDa
Gene ID 4150
NCBI Accession NM_002383, NP_002374
UniProt P56270
Pathways Chromatin Binding
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 477 AA

Restrictions For Research Use only
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Supplier Images
Western Blotting (WB) image for anti-MYC-Associated Zinc Finger Protein (Purine-Binding Transcription Factor) (MAZ) (N-Term) antibody (ABIN2780422) WB Suggested Anti-MAZ Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Posit...
Immunohistochemistry (IHC) image for anti-MYC-Associated Zinc Finger Protein (Purine-Binding Transcription Factor) (MAZ) (N-Term) antibody (ABIN2780422) Human Breast
Western Blotting (WB) image for anti-MYC-Associated Zinc Finger Protein (Purine-Binding Transcription Factor) (MAZ) (N-Term) antibody (ABIN2780422) Host: Mouse Target Name: MAZ Sample Tissue: Mouse Spleen Antibody Dilution: 1u...
Product cited in: Smits, Wurdinger, van het Hof, Drexhage, Geerts, Wesseling, Noske, Vandertop, de Vries, Reijerkerk: "Myc-associated zinc finger protein (MAZ) is regulated by miR-125b and mediates VEGF-induced angiogenesis in glioblastoma." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 26, Issue 6, pp. 2639-47, 2012 (PubMed).

Background publications Ray, Shakya, Ray: "Vascular endothelial growth factor expression in arthritic joint is regulated by SAF-1 transcription factor." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 178, Issue 3, pp. 1774-82, 2007 (PubMed).

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