ASH2L antibody (Middle Region)

Catalog No. ABIN2778325

The Rabbit Polyclonal anti-ASH2L antibody (ABIN2778325) specifically detects ASH2L in WB and IHC. The antibody is reactive with Human, Mouse, Rat, Dog, Horse, Cow, Guinea Pig and Rabbit samples.

Quick Overview for ASH2L antibody (Middle Region) (ABIN2778325)

Target: ASH2L (Set1/Ash2 Histone Methyltransferase Complex Subunit ASH2 (ASH2L))

Reactivity: Human, Mouse, Rat, Dog, Horse, Cow, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ASH2L antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-ASH2L Antibody

Binding Specificity: Middle Region

Purpose: ASH2L Antibody - middle region

Sequence: AAGSSGKGRG AKRKQQDGGT TGTTKKARSD PLFSAQRLPP HGYPLEHPFN

Predicted Reactivity: Cow: 86%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against ASH2L. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ASH2L

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP34202-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for ASH2L

Target: ASH2L (Set1/Ash2 Histone Methyltransferase Complex Subunit ASH2 (ASH2L))

Alternative Name: ASH2L

Background:

Targeted Subunit: ASH2

Background Information: ASH2L is a component of the Set1/Ash2 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3, but not if the neighboring 'Lys-9' residue is already methylated. The protein may function as a transcriptional regulator and play a role in hematopoiesis.

Gene Name: Ash2 (absent, small, or homeotic)-like (Drosophila)

Alternative Symbols: ASH2, Bre2, ASH2L1, ASH2L2

Protein Name: Set1/Ash2 histone methyltransferase complex subunit ASH2

Molecular Weight: 69kDa

Gene ID: 9070

NCBI Accession: NP_004665

UniProt: Q9UBL3