TCF7 antibody (N-Term)

Catalog No. ABIN2778373

Product Details anti-TCF7 Antibody

Target: TCF7 (Transcription Factor 7 (T-Cell Specific, HMG-Box) (TCF7))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TCF7 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: AGGGDDLGAP DELLAFQDEG EEQDDKSRDS AAGPERDLAE LKSSLVNESE

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against TCF7. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human TCF7

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TCF7

Target: TCF7 (Transcription Factor 7 (T-Cell Specific, HMG-Box) (TCF7))

Alternative Name: TCF7 (TCF7 Products)

Synonyms: TCF-1 antibody, AI465550 antibody, Tcf1 antibody, Xtcf-1 antibody, Xtcf1 antibody, tcf-1 antibody, tcf1 antibody, tcf7 antibody, transcription factor 7 antibody, transcription factor 7, T cell specific antibody, transcription factor 7 S homeolog antibody, TCF7 antibody, Tcf7 antibody, tcf7 antibody, tcf7.S antibody

Background: The protein encoded by this gene is a transcriptional activator that plays an important role in lymphocyte differentiation. This gene is expressed predominantly in T-cells. The encoded protein can bind an enhancer element and activate the CD3E gene, and it also may repress the CTNNB1 and TCF7L2 genes through a feedback mechanism. Several transcript variants encoding different isoforms have been found for this gene.
Protein Interaction Partner: UBC, SS18L1, DAZAP2,
Protein Size: 365

Molecular Weight: 40 kDa

Gene ID: 6932

Pathways: WNT Signaling