MLXIPL antibody (N-Term)
Quick Overview for MLXIPL antibody (N-Term) (ABIN2778415)
Target
See all MLXIPL AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- N-Term
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Purpose
- MLXIPL Antibody - N-terminal region
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Sequence
- MAGALAGLAA GLQVPRVAPS PDSDSDTDSE DPSLRRSAGG LLRSQVIHSG
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Predicted Reactivity
- Cow: 86%, Guinea Pig: 86%, Human: 100%, Mouse: 93%, Rat: 93%
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Characteristics
- This is a rabbit polyclonal antibody against MLXIPL. It was validated on Western Blot and immunohistochemistry.
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Purification
- Protein A purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human MLXIPL
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP39736-100UG
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1.0 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- prevent freeze-thaw cycles
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Storage
- 4 °C,-20 °C
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Storage Comment
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- MLXIPL (MLX Interacting Protein-Like (MLXIPL))
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Alternative Name
- MLXIPL
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Background
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Background Information: MLXIPL is a basic helix-loop-helix leucine zipper transcription factor of the Myc/Max/Mad superfamily. This protein forms a heterodimeric complex and binds and activates, in a glucose-dependent manner, carbohydrate response element (ChoRE) motifs in the promoters of triglyceride synthesis genes.
Gene Name: MLX interacting protein-like
Alternative Symbols: MIO, MLX, CHREBP, MONDOB, WBSCR14, WS-bHLH, bHLHd14
Protein Name: Carbohydrate-responsive element-binding protein
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Molecular Weight
- 63kDa
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Gene ID
- 51085
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UniProt
- Q9NP71
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Pathways
- Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process
Target
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