Cyclin D1 antibody (C-Term)

Catalog No. ABIN2778440

This anti-Cyclin D1 antibody is a Rabbit Polyclonal antibody detecting Cyclin D1 in WB. Suitable for Human, Mouse, Rat, Cow, Dog, Horse and Guinea Pig.

Quick Overview for Cyclin D1 antibody (C-Term) (ABIN2778440)

Target: Cyclin D1 (CCND1)

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cyclin D1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Cyclin D1 Antibody

Binding Specificity: C-Term

Sequence: PDCLRACQEQ IEALLESSLR QAQQNVDPKA TEEEGEVEEE AGLACTPTDV

Predicted Reactivity: Cow: 87%, Dog: 80%, Guinea Pig: 90%, Horse: 87%, Human: 100%, Mouse: 86%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against Ccnd1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide corresponding to a region of Mouse

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 295 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Cyclin D1

Target: Cyclin D1 (CCND1)

Alternative Name: Ccnd1

Background: Ccnd1 is essential for the control of the cell cycle at the G1/S (start) transition.
Alias Symbols: AI327039, Cyl-1, PRAD1, bcl-1, cD1
Protein Interaction Partner: Cdk4, Hspa8, Cdkn1a, RB1, HIST1H1B, Cdkn1b, Ppp1cc, Cdk6, Fbxo4, Cryab, Hdac1, Pura, Ctnnb1, Apc, Mybl2, Cdk2, Myc, Hspa1b,
Protein Size: 295

Molecular Weight: 33 kDa

Gene ID: 12443

NCBI Accession: NM_007631, NP_031657

UniProt: P25322

Pathways: PI3K-Akt Signaling, Cell Division Cycle, Mitotic G1-G1/S Phases, ER-Nucleus Signaling