SIRT5 antibody (C-Term)

Catalog No. ABIN2778619

This Rabbit Polyclonal antibody specifically detects SIRT5 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Goat, Rabbit, Guinea Pig, Dog, Horse and Zebrafish (Danio rerio)and has been mentioned in 1 publication.

Quick Overview for SIRT5 antibody (C-Term) (ABIN2778619)

Target: SIRT5 (Sirtuin 5 (SIRT5))

Reactivity: Human, Mouse, Rat, Cow, Goat, Rabbit, Guinea Pig, Dog, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SIRT5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SIRT5 Antibody

Binding Specificity: C-Term

Sequence: HCDLCLVVGT SSVVYPAAMF APQVAARGVP VAEFNTETTP ATNRFSHLIS

Predicted Reactivity: Cow: 86%, Dog: 93%, Goat: 100%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 86%, Rabbit: 86%, Rat: 93%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against SIRT5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human SIRT5

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 299 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-SIRT5 antibody (ABIN2778619)

Nagarajan, Ramanathan, Dhanapriya, Dineshkumar, Subramaniyan, Gopalakrishnan: "Impact of acute kidney injury on renal allograft survival." in: Renal failure, Vol. 39, Issue 1, pp. 40-44, (2016) (PubMed).

Target Details for SIRT5

Target: SIRT5 (Sirtuin 5 (SIRT5))

Alternative Name: SIRT5

Background: SIRT5 is included in class III of the sirtuin family which ischaracterized by a sirtuin core domain. Human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity.
Alias Symbols: SIR2L5
Protein Interaction Partner: SIRT3, UBC, HECW2, APP, RELA,
Protein Size: 299

Molecular Weight: 33 kDa

Gene ID: 23408

NCBI Accession: NM_006800, NP_112534

UniProt: Q5T295

Pathways: SARS-CoV-2 Protein Interactome