TUBB2A antibody (Middle Region)

Catalog No. ABIN2778647

Product Details anti-TUBB2A Antibody

Target: TUBB2A (Tubulin, beta 2A (TUBB2A))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TUBB2A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: AVNMVPFPRL HFFMPGFAPL TSRGSQQYRA LTVPELTQQM FDSKNMMAAC

Predicted Reactivity: Human: 100%, Mouse: 100%, Rat: 100%, Sheep: 100%

Characteristics: This is a rabbit polyclonal antibody against TUBB2A. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TUBB2A

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 445 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-TUBB2A antibody (ABIN2778647)

Zhang, Rataj, Simpson, Tong: "Crystal Structure of the SPOC Domain of the Arabidopsis Flowering Regulator FPA." in: PLoS ONE, Vol. 11, Issue 8, pp. e0160694, (2016) (PubMed).

Target Details for TUBB2A

Target: TUBB2A (Tubulin, beta 2A (TUBB2A))

Alternative Name: TUBB2A (TUBB2A Products)

Synonyms: TUBB antibody, TUBB2 antibody, dJ40E16.7 antibody, M(beta)2 antibody, Tubb2 antibody, TUBB2A antibody, tubb2a antibody, zgc:112335 antibody, tubulin beta 2A class IIa antibody, tubulin, beta 2A class IIA antibody, tubulin beta-2A chain antibody, tubulin, beta 2A class IIa antibody, TUBB2A antibody, Tubb2a antibody, LOC478701 antibody, LOC100079040 antibody, LOC100349792 antibody, LOC100599614 antibody, tubb2 antibody

Background: TUBB2A belongs to the tubulin family. Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain.
Alias Symbols: TUBB, TUBB2, dJ40E16.7
Protein Interaction Partner: HUWE1, UBC, TPT1, TP53, EMD, SUMO2, CDC20, CEP76, FAM96B, TUBGCP4, TUBGCP2, NEDD8, ASB4, RNF2, rev, TUBA1C, NSFL1C, UBXN1, TWF2, TUBB4B, PLAA, PAPSS2, YWHAE, TUFM, TUBA4A, QARS, PFKM, PCBP1, HK1, CAPN2, TUBB8, TUBB, LATS2, UPF2, EGFR, ADRB2, SOX2, CD81, P
Protein Size: 445

Molecular Weight: 49 kDa

Gene ID: 7280

NCBI Accession: NM_001069, NP_001060

UniProt: Q13885

Pathways: Microtubule Dynamics, M Phase