RBMS3 antibody (C-Term)

Catalog No. ABIN2778691

The Rabbit Polyclonal anti-RBMS3 antibody (ABIN2778691) specifically detects RBMS3 in WB. The antibody is reactive with Human, Mouse, Rat, Dog, Guinea Pig, Rabbit, Cow and Horse samples.

Quick Overview for RBMS3 antibody (C-Term) (ABIN2778691)

Target: RBMS3 (RNA Binding Motif, Single Stranded Interacting Protein 3 (RBMS3))

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Rabbit, Cow, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RBMS3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RBMS3 Antibody

Binding Specificity: C-Term

Purpose: RBMS3 Antibody - C-terminal region

Sequence: TAVSIEGVVA DTSPQTVAPS SQDTSGQQQQ IAVDTSNEHA PAYSYQQSKP

Predicted Reactivity: Cow: 79%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 79%, Rabbit: 100%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against RBMS3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human RBMS3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP40235-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for RBMS3

Target: RBMS3 (RNA Binding Motif, Single Stranded Interacting Protein 3 (RBMS3))

Alternative Name: RBMS3

Background:

Background Information: RBMS3 is a member of a small family of proteins which bind single stranded DNA/RNA. These proteins are characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS) that contain conserved motifs, RNP1 and RNP2, originally described in RNA binding proteins, and required for DNA binding. These proteins have been implicated in such diverse functions as DNA replication, gene transcription, cell cycle progression and apoptosis.The protein encoded by this gene is a member of a small family of proteins which bind single stranded DNA/RNA. These proteins are characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS) that contain conserved motifs, RNP1 and RNP2, originally described in RNA binding proteins, and required for DNA binding. These proteins have been implicated in such diverse functions as DNA replication, gene transcription, cell cycle progression and apoptosis. The encoded protein was isolated by virtue of its binding to an upstream element of the alpha2(I) collagen promoter. The observation that this protein localizes mostly in the cytoplasm suggests that it may be involved in a cytoplasmic function such as controlling RNA metabolism, rather than transcription. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene Name: RNA binding motif, single stranded interacting protein 3

Protein Name: RNA-binding motif, single-stranded-interacting protein 3

Molecular Weight: 46kDa

Gene ID: 27303

NCBI Accession: NP_001003792

UniProt: Q6XE24