DKC1 antibody (N-Term)

Catalog No. ABIN2778770

The Rabbit Polyclonal anti-DKC1 antibody (ABIN2778770) specifically detects DKC1 in WB. The antibody is reactive with Human, Mouse, Rat, Rabbit, Cow, Dog, Sheep, Zebrafish (Danio rerio), Guinea Pig, Horse, Goat and Saccharomyces cerevisiae samples.

Quick Overview for DKC1 antibody (N-Term) (ABIN2778770)

Target: DKC1 (Dyskeratosis Congenita 1, Dyskerin (DKC1))

Reactivity: Human, Mouse, Rat, Rabbit, Cow, Dog, Sheep, Zebrafish (Danio rerio), Guinea Pig, Horse, Goat, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DKC1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DKC1 Antibody

Binding Specificity: N-Term

Purpose: DKC1 Antibody - N-terminal region

Sequence: EFLIKPESKV AKLDTSQWPL LLKNFDKLNV RTTHYTPLAC GSNPLKREIG

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 79%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Yeast: 86%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against DKC1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human DKC1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP40357-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for DKC1

Target: DKC1 (Dyskeratosis Congenita 1, Dyskerin (DKC1))

Alternative Name: DKC1

Background:

Targeted Subunit: 4

Background Information: This gene is a member of the H/ACA snoRNPs (small nucleolar ribonucleoproteins) gene family. snoRNPs are involved in various aspects of rRNA processing and modification and have been classified into two families: C/D and H/ACA. The H/ACA snoRNPs also incl

Gene Name: Dyskeratosis congenita 1, dyskerin

Alternative Symbols: DKC, CBF5, DKCX, NAP57, NOLA4, XAP101

Protein Name: H/ACA ribonucleoprotein complex subunit 4

Molecular Weight: 58kDa

Gene ID: 1736

NCBI Accession: NP_001354

UniProt: O60832

Pathways: Telomere Maintenance