SRGN antibody (N-Term)

Catalog No. ABIN2778808

The Rabbit Polyclonal anti-SRGN antibody (ABIN2778808) specifically detects SRGN in WB. The antibody is reactive with Human, Mouse, Rat and Rabbit samples.

Quick Overview for SRGN antibody (N-Term) (ABIN2778808)

Target: SRGN (serglycin (SRGN))

Reactivity: Human, Mouse, Rat, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SRGN antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SRGN Antibody

Binding Specificity: N-Term

Purpose: SRGN Antibody - N-terminal region

Sequence: LLKCSRLVLA LALILVLESS VQGYPTRRAR YQWVRCNPDS NSANCLEEKG

Predicted Reactivity: Human: 100%, Mouse: 91%, Rabbit: 85%, Rat: 91%

Characteristics: This is a rabbit polyclonal antibody against SRGN. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP40415-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for SRGN

Target: SRGN (serglycin (SRGN))

Alternative Name: SRGN

Background:

Background Information: SRGN is a protein best known as a hematopoietic cell granule proteoglycan. Proteoglycans stored in the secretory granules of many hematopoietic cells also contain a protease-resistant peptide core, which may be important for neutralizing hydrolytic enzymes. SRGN was found to be associated with the macromolecular complex of granzymes and perforin, which may serve as a mediator of granule-mediated apoptosis.

Gene Name: Serglycin

Alternative Symbols: PPG, PRG, PRG1

Protein Name: Serglycin

Molecular Weight: 15kDa

Gene ID: 5552

NCBI Accession: NP_002718

UniProt: P10124

Pathways: Maintenance of Protein Location