SRP19 antibody (Middle Region)

Catalog No. ABIN2778840

There is 1 publication for this product available. The Rabbit Polyclonal anti-SRP19 antibody is suitable to detect SRP19 in samples from Human, Mouse, Rat, Rabbit, Zebrafish (Danio rerio), Cow, Dog, Horse and Pig. It has been validated for WB and IHC.

Quick Overview for SRP19 antibody (Middle Region) (ABIN2778840)

Target: SRP19 (Signal Recognition Particle 19kDa (SRP19))

Reactivity: Human, Mouse, Rat, Rabbit, Zebrafish (Danio rerio), Cow, Dog, Horse, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SRP19 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-SRP19 Antibody

Binding Specificity: Middle Region

Purpose: SRP19 Antibody - middle region

Sequence: LCLVQFPSRK SVMLYAAEMI PKLKTRTQKT GGADQSLQQG EGSKKGKGKK

Predicted Reactivity: Cow: 93%, Dog: 93%, Horse: 93%, Human: 100%, Mouse: 92%, Pig: 93%, Rabbit: 85%, Rat: 92%, Zebrafish: 77%

Characteristics: This is a rabbit polyclonal antibody against SRP19. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SRP19

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8111716

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-SRP19 antibody (ABIN2778840)

Arana-Argáez, Delgado-Rizo, Pizano-Martínez, Martínez-Garcia, Martín-Márquez, Muñoz-Gómez, Petri, Armendáriz-Borunda, Espinosa-Ramírez, Zúñiga-Tamayo, Herrera-Esparza, Vázquez-Del Mercado: "Inhibitors of MAPK pathway ERK1/2 or p38 prevent the IL-1{beta}-induced up-regulation of SRP72 autoantigen in Jurkat cells." in: The Journal of biological chemistry, Vol. 285, Issue 43, pp. 32824-33, (2010) (PubMed).

Target Details for SRP19

Target: SRP19 (Signal Recognition Particle 19kDa (SRP19))

Alternative Name: SRP19

Background:

Background Information: SRP19 belongs to the SRP19 family. It is signal-recognition-particle assembly and binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP.

Gene Name: Signal recognition particle 19 kDa

Protein Name: Signal recognition particle 19 kDa protein

Molecular Weight: 16kDa

Gene ID: 6728

NCBI Accession: NP_003126

UniProt: P09132

Pathways: SARS-CoV-2 Protein Interactome