SRP54 antibody (Middle Region)

Catalog No. ABIN2778842

The Rabbit Polyclonal anti-SRP54 antibody is suitable to detect SRP54 in samples from Human, Mouse, Rat, Dog, Zebrafish (Danio rerio), Cow, Guinea Pig, Horse, Rabbit and Goat. It has been validated for WB and IP.

Quick Overview for SRP54 antibody (Middle Region) (ABIN2778842)

Target: SRP54 (Signal Recognition Particle 54kDa (SRP54))

Reactivity: Human, Mouse, Rat, Dog, Zebrafish (Danio rerio), Cow, Guinea Pig, Horse, Rabbit, Goat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SRP54 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-SRP54 Antibody

Binding Specificity: Middle Region

Purpose: SRP54 Antibody - middle region

Sequence: ENFEIIIVDT SGRHKQEDSL FEEMLQVANA IQPDNIVYVM DASIGQACEA

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against SRP54. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SRP54

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP40458-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for SRP54

Target: SRP54 (Signal Recognition Particle 54kDa (SRP54))

Alternative Name: SRP54

Background:

Background Information: SRP54 belongs to the GTP-binding SRP family. It binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein).

Gene Name: Signal recognition particle 54 kDa

Alternative Symbols: SCN8

Protein Name: Signal recognition particle 54 kDa protein

Molecular Weight: 56kDa

Gene ID: 6729

NCBI Accession: NP_003127

UniProt: P61011

Pathways: SARS-CoV-2 Protein Interactome