RNMT antibody (C-Term)

Catalog No. ABIN2778871

This Rabbit Polyclonal antibody specifically detects RNMT in WB. It exhibits reactivity toward Human, Rat, Cow, Dog, Mouse, Horse, Guinea Pig and Rabbit.

Quick Overview for RNMT antibody (C-Term) (ABIN2778871)

Target: RNMT (RNA Guanine-7 Methyltransferase (RNMT))

Reactivity: Human, Rat, Cow, Dog, Mouse, Horse, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RNMT antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RNMT Antibody

Binding Specificity: C-Term

Purpose: RNMT Antibody - C-terminal region

Sequence: RRLEASETES FGNEIYTVKF QKKGDYPLFG CKYDFNLEGV VDVPEFLVYF

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 92%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against RNMT. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human RNMT

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8110987

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for RNMT

Target: RNMT (RNA Guanine-7 Methyltransferase (RNMT))

Alternative Name: RNMT

Background:

Background Information: RNMT belongs to the mRNA cap methyltransferase family. RNMT is a mRNA-capping methyltransferase that methylates the N7 position of the added guanosine to the 5'-cap structure of mRNAs. It binds RNA containing 5'-terminal GpppC.

Gene Name: RNA (guanine-7-) methyltransferase

Alternative Symbols: MET, Met, CMT1, cm1p, hMet, CMT1c, hCMT1, RG7MT1

Protein Name: mRNA cap guanine-N7 methyltransferase

Molecular Weight: 55kDa

Gene ID: 8731

NCBI Accession: NP_003790

UniProt: O43148