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HNRPDL antibody (C-Term)

HNRPDL Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Zebrafish (Danio rerio), Rabbit WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2778938
  • Target See all HNRPDL Antibodies
    HNRPDL (Heterogeneous Nuclear Ribonucleoprotein D-Like (HNRPDL))
    Binding Specificity
    • 15
    • 8
    • 7
    • 6
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 30
    • 30
    • 14
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Zebrafish (Danio rerio), Rabbit
    Host
    • 45
    Rabbit
    Clonality
    • 45
    Polyclonal
    Conjugate
    • 14
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This HNRPDL antibody is un-conjugated
    Application
    • 34
    • 20
    • 13
    • 13
    • 6
    • 5
    • 3
    • 3
    • 2
    Western Blotting (WB)
    Sequence
    YSGYGGYDYT GYNYGNYGYG QGYADYSGQQ STYGKASRGG GNHQNNYQPY
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%
    Characteristics
    This is a rabbit polyclonal antibody against HNRPDL. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C terminal region of human HNRPDL
    Top Product
    Discover our top product HNRPDL Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 420 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Li, Johansson, Glahder, Mossberg, Schwartz: "Suppression of HPV-16 late L1 5'-splice site SD3632 by binding of hnRNP D proteins and hnRNP A2/B1 to upstream AUAGUA RNA motifs." in: Nucleic acids research, Vol. 41, Issue 22, pp. 10488-508, (2013) (PubMed).

    Anderson, Lin, Xiao, Stoilov, Burge, Black: "The cardiotonic steroid digitoxin regulates alternative splicing through depletion of the splicing factors SRSF3 and TRA2B." in: RNA (New York, N.Y.), Vol. 18, Issue 5, pp. 1041-9, (2012) (PubMed).

  • Target
    HNRPDL (Heterogeneous Nuclear Ribonucleoprotein D-Like (HNRPDL))
    Alternative Name
    HNRPDL (HNRPDL Products)
    Synonyms
    wu:fa11d08 antibody, zgc:66169 antibody, hnRNP DL antibody, Hnrpdl antibody, AA407431 antibody, AA959857 antibody, D5Ertd650e antibody, D5Wsu145e antibody, JKTBP antibody, hnRNP-DL antibody, hnRNP antibody, hnrpdl antibody, hnrpdl-a antibody, jktbp antibody, jktbp2 antibody, laauf1 antibody, HNRNP antibody, HNRPDL antibody, JKTBP2 antibody, laAUF1 antibody, hnRNP D-like B antibody, hnRNP DL-B antibody, hnrnpdl-b antibody, hnrpdl-b antibody, heterogeneous nuclear ribonucleoprotein D-like antibody, heterogeneous nuclear ribonucleoprotein D like antibody, heterogeneous nuclear ribonucleoprotein D like L homeolog antibody, heterogeneous nuclear ribonucleoprotein D like S homeolog antibody, hnrpdl antibody, HNRNPDL antibody, Hnrnpdl antibody, hnrnpdl.L antibody, LOC100351670 antibody, LOC101120922 antibody, hnrnpdl.S antibody
    Background
    HNRPDL belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. HNRPDL has two RRM domains that bind to RNAs. Two alternatively spliced transcript variants have been described for this gene. One of the variants is probably not translated because the transcript is a candidate for nonsense-mediated mRNA decay. The protein is similar to its family member HNRPD.
    Alias Symbols: HNRNP, JKTBP, JKTBP2, laAUF1, HNRPDL
    Protein Interaction Partner: SPRTN, SUMO2, SUMO3, UBC, RPA3, RPA2, RPA1, ERG, EED, RNF2, rev, PARK2, FBXO6, TARDBP, HMGA1, ITGA4, IL7R, IFIT3, IFIT2, FN1, CSNK2A1, BARD1, EEF2, EEF1A1, DDX3X, ATP6V1B1, HNRNPA3, WIPF2, RMDN3, MRPS16, UBE2S, LSM14A, RPL36, U2AF2, HNRNPUL1, HNRNPA0, HNR
    Protein Size: 420
    Molecular Weight
    46 kDa
    Gene ID
    9987
    NCBI Accession
    NM_005463, NP_005454
    UniProt
    O14979
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