PPIE antibody (Middle Region)

Catalog No. ABIN2778968

This anti-PPIE antibody is a Rabbit Polyclonal antibody detecting PPIE in WB and IHC. Suitable for Human, Mouse, Rat, Dog, Guinea Pig, Saccharomyces cerevisiae, Cow, Horse, Pig, Rabbit and Sheep.

Quick Overview for PPIE antibody (Middle Region) (ABIN2778968)

Target: PPIE (Peptidylprolyl Isomerase E (Cyclophilin E) (PPIE))

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Saccharomyces cerevisiae, Cow, Horse, Pig, Rabbit, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPIE antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-PPIE Antibody

Binding Specificity: Middle Region

Sequence: KKFSGKTLEE NKEEEGSEPP KAETQEGEPI AKKARSNPQV YMDIKIGNKP

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 93%, Sheep: 100%, Yeast: 100%

Characteristics: This is a rabbit polyclonal antibody against PPIE. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PPIE

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 301 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PPIE

Target: PPIE (Peptidylprolyl Isomerase E (Cyclophilin E) (PPIE))

Alternative Name: PPIE

Background: PPIE is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein contains a highly conserved cyclophilin (CYP) domain as well as an RNA-binding domain. It was shown to possess PPIase and protein folding activities and also exhibit RNA-binding activity. Three alternatively spliced transcript variants encoding distinct isoforms have been observed.The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein contains a highly conserved cyclophilin (CYP) domain as well as an RNA-binding domain. It was shown to possess PPIase and protein folding activities and also exhibit RNA-binding activity. Three alternatively spliced transcript variants encoding distinct isoforms have been observed.
Alias Symbols: CYP33, CYP-33
Protein Interaction Partner: XAB2, BMI1, UBC, EIF4A3, MAGOH, SF3A2, HHV8GK18_gp81, SUMO2, Prpf8, Cdc5l, Snw1, KMT2A, PHYHIP,
Protein Size: 301

Molecular Weight: 33 kDa

Gene ID: 10450

NCBI Accession: NM_006112, NP_006103

UniProt: Q9UNP9