PAIP1 antibody (N-Term)

Catalog No. ABIN2778987

There is 1 publication for this product available. The Rabbit Polyclonal anti-PAIP1 antibody is suitable to detect PAIP1 in samples from Human, Mouse, Rat, Cow, Horse, Dog, Guinea Pig and Rabbit. It has been validated for WB.

Quick Overview for PAIP1 antibody (N-Term) (ABIN2778987)

Target: PAIP1 (Poly(A) Binding Protein Interacting Protein 1 (PAIP1))

Reactivity: Human, Mouse, Rat, Cow, Horse, Dog, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PAIP1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PAIP1 Antibody

Binding Specificity: N-Term

Purpose: PAIP1 Antibody - N-terminal region

Sequence: MSDGFDRAPE QTRPLRAPPS SQDKIPQQNS ESAMAKPQVV VAPVLMSKLS

Predicted Reactivity: Cow: 85%, Dog: 86%, Guinea Pig: 93%, Horse: 79%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against PAIP1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PAIP1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8108457

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-PAIP1 antibody (ABIN2778987)

Fortna, Kim, MacLaren, Marshall, Hahn, Meltesen, Brenton, Hink, Burgers, Hernandez-Boussard, Karimpour-Fard, Glueck, McGavran, Berry, Pollack, Sikela: "Lineage-specific gene duplication and loss in human and great ape evolution." in: PLoS biology, Vol. 2, Issue 7, pp. E207, (2004) (PubMed).

Target Details for PAIP1

Target: PAIP1 (Poly(A) Binding Protein Interacting Protein 1 (PAIP1))

Alternative Name: PAIP1

Background:

Background Information: PAIP1 interacts with poly(A)-binding protein and with the cap-binding complex eIF4A. It is involved in translational initiation and protein biosynthesis. Overexpression of this gene in COS7 cells stimulates translation.The protein encoded by this gene interacts with poly(A)-binding protein and with the cap-binding complex eIF4A. It is involved in translational initiation and protein biosynthesis. Overexpression of this gene in COS7 cells stimulates translation. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified.The protein encoded by this gene interacts with poly(A)-binding protein and with the cap-binding complex eIF4A. It is involved in translational initiation and protein biosynthesis. Overexpression of this gene in COS7 cells stimulates translation. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified.

Gene Name: Poly(A) binding protein interacting protein 1

Alternative Symbols: MGC12360

Protein Name: Polyadenylate-binding protein-interacting protein 1

Molecular Weight: 46kDa

Gene ID: 10605

NCBI Accession: NP_877590

UniProt: Q9H074