FARS2 antibody (N-Term)

Catalog No. ABIN2779002

Product Details anti-FARS2 Antibody

Target: FARS2 (Phenylalanine-tRNA Synthetase 2 (Mitochondrial) (FARS2))

Binding Specificity: N-Term

Reactivity: Human, Rat, Mouse, Horse, Rabbit, Dog, Guinea Pig, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FARS2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: VELLGKSYPQ DDHSNLTRKV LTRVGRNLHN QQHHPLWLIK ERVKEHFYKQ

Predicted Reactivity: Cow: 93%, Dog: 92%, Guinea Pig: 85%, Horse: 83%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against FARS2. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human FARS2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 451 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for FARS2

Target: FARS2 (Phenylalanine-tRNA Synthetase 2 (Mitochondrial) (FARS2))

Alternative Name: FARS2 (FARS2 Products)

Synonyms: 2810431B21Rik antibody, 6720478K01Rik antibody, Fars1 antibody, COXPD14 antibody, FARS1 antibody, HSPC320 antibody, PheRS antibody, dJ520B18.2 antibody, phenylalanine-tRNA synthetase 2 (mitochondrial) antibody, phenylalanyl-tRNA synthetase 2, mitochondrial antibody, Fars2 antibody, FARS2 antibody

Background: Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. FARS2 is a phenylalanine-tRNA synthetase (PheRS) localized to the mitochondrion which consists of a single polypeptide chain, unlike the (alpha-beta)2 structure of the prokaryotic and eukaryotic cytoplasmic forms of PheRS. Structure analysis and catalytic properties indicate mitochondrial PheRSs may constitute a class of PheRS distinct from the enzymes found in prokaryotes and in the eukaryotic cytoplasm.Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. FARS1 encodes a mitochondrially-located phenylalanine-tRNA synthetase (PheRS) which consists of a single polypeptide chain unlike the (alpha-beta)2 structure of the prokaryotic and eukaryotic cytoplasmic forms of PheRS. Structure analysis and catalytic properties indicate mitochondrial PheRSs may constitute a class of PheRS distinct from the enzymes found in prokaryotes and the eukaryotic cytoplasm.
Alias Symbols: FARS1, HSPC320, PheRS, dJ520B18.2
Protein Interaction Partner: TRIM27, KRT31, KRT13, RCBTB2, NOTCH2NL, KRTAP10-3, KRTAP10-5, KRTAP10-9, KRTAP10-7, KRT40, CMTM5, HMBOX1, TRIM54, AGTRAP, ADAMTSL4, APPL1, IKZF3, MID2, CALCOCO2, STX11, MKRN3, TFCP2, TADA2A, SUMO1, UBC, NEDD8, CUL3, ISG15, ICT1, USP45, G3BP2,
Protein Size: 451

Molecular Weight: 50 kDa

Gene ID: 10667

NCBI Accession: NM_006567, NP_006558

UniProt: O95363