HSD17B11 antibody (Middle Region)
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- Target See all HSD17B11 Antibodies
- HSD17B11 (Hydroxysteroid (17-Beta) Dehydrogenase 11 (HSD17B11))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Rat, Mouse, Cow, Dog, Horse, Rabbit, Pig
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This HSD17B11 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- IYSAAKKVKE EVGDVSILVN NAGVVYTADL FATQDPQIEK TFEVNVLAHF
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 100%
- Characteristics
- This is a rabbit polyclonal antibody against Hsd17b11. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product HSD17B11 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 298 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- HSD17B11 (Hydroxysteroid (17-Beta) Dehydrogenase 11 (HSD17B11))
- Alternative Name
- Hsd17b11 (HSD17B11 Products)
- Synonyms
- 17BHSD11 antibody, DHRS8 antibody, PAN1B antibody, RETSDR2 antibody, SDR16C2 antibody, Dhrs8 antibody, HSD17B13 antibody, MGC84756 antibody, HSD17B11 antibody, Pan1b antibody, SDR2 antibody, retSDR2 antibody, 17-beta-HSD 11 antibody, 17-beta-HSD XI antibody, 17bHSD11 antibody, 17betaHSD11 antibody, 17betaHSDXI antibody, hydroxysteroid 17-beta dehydrogenase 11 antibody, hydroxysteroid (17-beta) dehydrogenase 11 antibody, hydroxysteroid (17-beta) dehydrogenase 11 L homeolog antibody, estradiol 17-beta-dehydrogenase 11 antibody, HSD17B11 antibody, Hsd17b11 antibody, hsd17b11.L antibody, hsd17b11 antibody, LOC100348005 antibody, LOC100520923 antibody
- Background
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Hsd17b11 can convert androstan-3-alpha,17-beta-diol (3-alpha-diol) to androsterone in vitro, suggesting that it may participate in androgen metabolism during steroidogenesis. Hsd17b11 may act by metabolizing compounds that stimulate steroid synthesis and/or by generating metabolites that inhibit it. It has no activity toward DHEA (dehydroepiandrosterone), or A-dione (4-androste-3,17-dione), and only a slight activity toward testosterone to A-dione.
Alias Symbols: Dhrs8, Pan1b, SDR2, retSDR2
Protein Interaction Partner: Eed,
Protein Size: 298 - Molecular Weight
- 33 kDa
- Gene ID
- 114664
- NCBI Accession
- NM_053262, NP_444492
- UniProt
- Q9EQ06
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