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HSD17B11 antibody (Middle Region)

HSD17B11 Reactivity: Human, Rat, Mouse, Cow, Dog, Horse, Rabbit, Pig WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2779101
  • Target See all HSD17B11 Antibodies
    HSD17B11 (Hydroxysteroid (17-Beta) Dehydrogenase 11 (HSD17B11))
    Binding Specificity
    • 15
    • 9
    • 8
    • 6
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 38
    • 17
    • 7
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Rat, Mouse, Cow, Dog, Horse, Rabbit, Pig
    Host
    • 53
    • 1
    Rabbit
    Clonality
    • 55
    Polyclonal
    Conjugate
    • 21
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This HSD17B11 antibody is un-conjugated
    Application
    • 29
    • 28
    • 18
    • 13
    • 13
    • 5
    • 3
    • 2
    • 1
    Western Blotting (WB)
    Sequence
    IYSAAKKVKE EVGDVSILVN NAGVVYTADL FATQDPQIEK TFEVNVLAHF
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 100%
    Characteristics
    This is a rabbit polyclonal antibody against Hsd17b11. It was validated on Western Blot.
    Purification
    Affinity Purified
    Top Product
    Discover our top product HSD17B11 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 298 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    HSD17B11 (Hydroxysteroid (17-Beta) Dehydrogenase 11 (HSD17B11))
    Alternative Name
    Hsd17b11 (HSD17B11 Products)
    Synonyms
    17BHSD11 antibody, DHRS8 antibody, PAN1B antibody, RETSDR2 antibody, SDR16C2 antibody, Dhrs8 antibody, HSD17B13 antibody, MGC84756 antibody, HSD17B11 antibody, Pan1b antibody, SDR2 antibody, retSDR2 antibody, 17-beta-HSD 11 antibody, 17-beta-HSD XI antibody, 17bHSD11 antibody, 17betaHSD11 antibody, 17betaHSDXI antibody, hydroxysteroid 17-beta dehydrogenase 11 antibody, hydroxysteroid (17-beta) dehydrogenase 11 antibody, hydroxysteroid (17-beta) dehydrogenase 11 L homeolog antibody, estradiol 17-beta-dehydrogenase 11 antibody, HSD17B11 antibody, Hsd17b11 antibody, hsd17b11.L antibody, hsd17b11 antibody, LOC100348005 antibody, LOC100520923 antibody
    Background
    Hsd17b11 can convert androstan-3-alpha,17-beta-diol (3-alpha-diol) to androsterone in vitro, suggesting that it may participate in androgen metabolism during steroidogenesis. Hsd17b11 may act by metabolizing compounds that stimulate steroid synthesis and/or by generating metabolites that inhibit it. It has no activity toward DHEA (dehydroepiandrosterone), or A-dione (4-androste-3,17-dione), and only a slight activity toward testosterone to A-dione.
    Alias Symbols: Dhrs8, Pan1b, SDR2, retSDR2
    Protein Interaction Partner: Eed,
    Protein Size: 298
    Molecular Weight
    33 kDa
    Gene ID
    114664
    NCBI Accession
    NM_053262, NP_444492
    UniProt
    Q9EQ06
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