A2BP1 antibody (N-Term)

Catalog No. ABIN2779140

The Rabbit Polyclonal anti-A2BP1 antibody is suitable to detect A2BP1 in samples from Human, Rat, Mouse, Cow, Dog, Horse, Guinea Pig, Pig and Rabbit. It has been validated for WB.

Quick Overview for A2BP1 antibody (N-Term) (ABIN2779140)

Target: A2BP1 (Ataxin 2-Binding Protein 1 (A2BP1))

Reactivity: Human, Rat, Mouse, Cow, Dog, Horse, Guinea Pig, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This A2BP1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-A2BP1 Antibody

Binding Specificity: N-Term

Purpose: A2BP1 Antibody - N-terminal region

Sequence: SAQTVSGTAT QTDDAAPTDG QPQTQPSENT ENKSQPKRLH VSNIPFRFRD

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against A2BP1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human A2BP1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP40921-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for A2BP1

Target: A2BP1 (Ataxin 2-Binding Protein 1 (A2BP1))

Alternative Name: A2BP1

Background:

Background Information: Ataxin-2 binding protein 1(A2BP1) has an RNP motif that is highly conserved among RNA-binding proteins. This protein binds to the C-terminus of ataxin-2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2). Ataxin-2 is the gene product of the SCA2 gene which causes familial neurodegenerative diseases. Ataxin-2 binding protein 1 and ataxin-2 are both localized in the trans-Golgi network. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been found but their full length nature has not been determined.

Gene Name: RNA binding protein, fox-1 homolog (C. elegans) 1

Alternative Symbols: 2BP1, FOX1, A2BP1, FOX-1, HRNBP1

Protein Name: RNA binding protein fox-1 homolog 1

Molecular Weight: 43kDa

Gene ID: 54715

NCBI Accession: NP_061193

UniProt: Q9NWB1