ELL antibody (Middle Region)

Catalog No. ABIN486784

This Rabbit Polyclonal antibody specifically detects ELL in WB. It exhibits reactivity toward Human and Dog.It has been mentioned in 1 publication

Quick Overview for ELL antibody (Middle Region) (ABIN486784)

Target: ELL (Elongation Factor RNA Polymerase II (ELL))

Reactivity: Human, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ELL antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ELL Antibody

Binding Specificity: Middle Region

Purpose: ELL Antibody - middle region

Sequence: TDCAQPSRPH GSPSRSKPKK KSKKHKDKER AAEDKPRAQL PDCAPATHAT

Predicted Reactivity: Dog: 86%, Human: 100%

Characteristics: This is a rabbit polyclonal antibody against ELL. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ELL

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP30106-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-ELL antibody (ABIN486784)

Wang, Xu, Han, Shi, Luo, Jiang, Lin, Huang, Xia, Guan: "High incidence of hepatitis B virus infection in B-cell subtype non-Hodgkin lymphoma compared with other cancers." in: Cancer, Vol. 109, Issue 7, pp. 1360-4, (2007) (PubMed).

Target Details for ELL

Target: ELL (Elongation Factor RNA Polymerase II (ELL))

Alternative Name: ELL

Background:

Background Information: ELL ia an elongation factor that can increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA.

Gene Name: Elongation factor RNA polymerase II

Alternative Symbols: MEN, ELL1, PPP1R68, C19orf17

Protein Name: RNA polymerase II elongation factor ELL

Molecular Weight: 68kDa

Gene ID: 8178

NCBI Accession: NP_006523

UniProt: P55199